Cancer family · grouped by EvidenceHelix from study titles

Multiple or not classified from the title: 48 studies

Public cancer genomics studies in this group, with the collection each belongs to. Open a study for its description, citation and original source links.

• Appendiceal Cancer (MSK, J Clin Oncol 2022)

  Targeted sequencing of 273 appendiceal tumor/normal pairs via MSK-IMPACT platform.

  Multiple or not classified from the titleMSK studiesSource code apadPubMed 1

• BRAF Fusions - ARCHER Clinical Sequencing Cohort (MSK, Clin Cancer Res 2024)

  Targeted sequencing of 107 clinical cases via ARCHER to characterize the structure and impact of BRAF fusions on clinical course in a tumor-agnostic approach. This study is part of a broader analysis and is complement…

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• BRAF Fusions - IMPACT Clinical Sequencing Cohort (MSK, Clin Cancer Res 2024)

  Targeted sequencing of 105 clinical cases via MSK-IMPACT to characterize the structure and impact of BRAF fusions on clinical course in a tumor-agnostic approach. This study is part of a broader analysis and is comple…

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• Cancer Cell Line Encyclopedia (Broad, 2019)

  Cancer Cell Line Encyclopedia from the Broad Institute and Novartis, updated 2019. Data downloaded from the Broad CCLE Portal (https://portals.broadinstitute.org/ccle/data). For more info about the proteomics data, se…

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 2

• Cancer Cell Line Encyclopedia (Broad, Nat Rev Cancer 2025)

  Whole genome and whole exome sequencing of 1,981 pancancer samples from the Cancer Cell Line Encyclopedia (CCLE). CCLE from Broad Institute and Novartis, 2025 (25Q3) update. Data downloaded from the Depmap Portal (htt…

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Cancer Cell Line Encyclopedia (Genentech, Nat biotech 2014)

  Single-nucleotide polymorphism (SNP) array analysis and RNA sequencing and of 675 mixed human cancer cell lines from the Cancer Cell Line Encyclopedia.

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Cancer Therapy and Clonal Hematopoiesis (MSK, Blood Adv 2023)

  Targeted sequencing of 47,532 patient samples with mixed tumor types and their matched normals to identify clonal hematopoiesis mutations using MSK-IMPACT.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• Cancer Therapy and Clonal Hematopoiesis (MSK, Clin Cancer Res 2022)

  Clonal hematopoiesis mutations identified in blood samples from patients whose tumor-blood pairs were analyzed using MSK-IMPACT.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• Cancer Therapy and Clonal Hematopoiesis (MSK, Nat Genet 2020)

  Clonal hematopoiesis mutations identified in blood samples from 24,146 patients whose tumor-blood pairs were analyzed using MSK-IMPACT.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• Cerebrospinal Fluid Circulating Tumor DNA (MSK, Acta Neuropathol Commun 2024)

  Targeted sequencing of 1,007 cerebrospinal fluid circulating tumor DNA from patients with central nervous system tumors using MSK-IMPACT and their matched normals.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• China Pan-cancer (OrigiMed, Nature 2022)

  Landscape of genomic alterations in 10,194 solid tumors from the Chinese population

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Insulinoma (Shanghai, Nat Commun 2013)

  Whole exome sequencing of 10 benign insulinoma tumor/normal pairs.

  Multiple or not classified from the titleOther published and consortium studiesSource code panetPubMed 1

• Merged Cohort of LGG and GBM (TCGA, Cell 2016)

  Whole exome sequencing of 1,122 LGG and GBM tumor/normal pairs.

  Multiple or not classified from the titleTCGA (other releases)Source code difgPubMed 1

• Metastatic Solid Cancers (UMich, Nature 2017)

  Whole-exome and -transcriptome sequencing of 500 adult patients with metastatic solid tumor/primary normal pairs of diverse lineage and biopsy site.

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Mixed cfDNA (MSK, Nature Medicine 2019)

  Targeted sequencing of 248 samples from 124 patients' cfDNA/WBC and tumor/normal pairs.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• Mixed Tumors - MiMSI Cohort (MSK, Nat Commun 2024)

  Targeted sequencing of 5,033 clinical cases and their matched normals via MSK-IMPACT, with pathologist-confirmed orthogonal MMR IHC data.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• Mixed Tumors Selpercatinib RET Trial (MSK, Nat Commun. 2022)

  Targeted sequencing of Selpercatinib treated RET-driven solid cancers.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• MSK ctDNA Sequencing Cohort (MSK, Nature Medicine 2024)

  Targeted sequencing of 5,567 cancer patient ctDNA samples via MSK-ACCESS. This data is available under the Creative Commons BY-NC-ND 4.0 license (https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en).

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• MSK Make-An-IMPACT (MSK, Clin Cancer Res 2023)

  Targeted sequencing of 167 patients with Histiocytosis and Germ Cell Tumors using MSK-IMPACT, MSK-IMPACT-Heme, and MSK-ACCESS platforms.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• MSK MetTropism (MSK, Cell 2021)

  MSK-MET (Memorial Sloan Kettering - Metastatic Events and Tropisms) is a pan-cancer cohort of tumor genomic and clinical outcome data from 25,000 patients. The dataset identifies associations between tumor genomic alt…

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• MSK-CHORD (MSK, Nature 2024)

  Targeted sequencing of 25040 tumors from 24950 patients and their matched normals via MSK-IMPACT, along with clinical annotations, some of which are derived from natural language processing (denoted NLP). This data is…

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• MSK-IMPACT 50K Clinical Sequencing Cohort (MSK, Cancer Cell 2026)

  MSK-50K (Memorial Sloan Kettering - 50,000 patients) is a pan-cancer clinical sequencing cohort of 54,331 tumors and their matched normal samples, profiled using MSK-IMPACT. The dataset includes somatic mutations, gen…

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• MSK-IMPACT and MSK-ACCESS Mixed Cohort (MSK, Nat Commun 2021)

  Targeted sequencing of 1446 Tumor and cfDNA samples (1440 with matched normals) from MSK-IMPACT and MSK-ACCESS.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• MSK-IMPACT Clinical Sequencing Cohort (MSK, Nat Med 2017)

  Targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• MSK-IMPACT Heme Tumors (MSK, 2022)

  Targeted sequencing of 2383 myeloid and lymphoid neoplasms and their matched normals via MSK-IMPACT Heme panel.

  Multiple or not classified from the titleMSK studiesSource code mixed

• MSS Mixed Solid Tumors (Broad/Dana-Farber, Nat Genet 2018)

  Whole exome sequencing of tumor/normal pairs and corresponding clinical outcomes from patients treated with immune checkpoint inhibitors across multiple cancer types including melanoma, non-small cell lung cancer, hea…

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Myelodysplasia (UTokyo, Nature 2011)

  Whole exome sequencing of 29 myelodysplasia tumor/normal pairs.

  Multiple or not classified from the titleOther published and consortium studiesSource code mdsPubMed 1

• NCI-60 Cell Lines (NCI, Cancer Res 2012)

  Whole-exome sequencing of 67 samples by NCI-60 cell line project; raw data at CellMiner (http://discover.nci.nih.gov/cellminer/loadDownload.do).

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Non-Small Cell Cancer (MSK, Cancer Discov 2017)

  Targeted sequencing of 860 patients with metastatic lung adenocarcinoma

  Multiple or not classified from the titleMSK studiesSource code luadPubMed 1

• Normal Fibroblasts (UCSF, BioRxiv 2024)

  Whole exome and targeted sequencing data of 23 normal fibroblast samples from human skin. The study is part of a broader analysis involving three distinct cell types, with findings stratified accordingly (see related…

  Multiple or not classified from the titleOther published and consortium studiesSource code skinPubMed 1

• Normal Keratinocytes (UCSF, BioRxiv 2024)

  Whole exome and targeted sequencing data of 137 normal keratinocytes samples from human skin. The study is part of a broader analysis involving three distinct cell types, with findings stratified accordingly (see rela…

  Multiple or not classified from the titleOther published and consortium studiesSource code skinPubMed 1

• Normal Melanocytes (UCSF, Nature 2020)

  Whole exome sequencing and targeted sequencing data of 308 normal melanocytes samples from human skin. In addition to data retrieved from four different articles, the study is part of a broader analysis involving thre…

  Multiple or not classified from the titleOther published and consortium studiesSource code skinPubMed 4

• Oral Squamous Cell Carcinoma (MD Anderson, Cancer Discov 2013)

  Whole-exome sequencing of 40 oral squamous cell carcinoma tumor/normal sample pairs.

  Multiple or not classified from the titleOther published and consortium studiesSource code hnscPubMed 1

• Pan-cancer Analysis of Advanced and Metastatic Tumors (BCGSC, Nature Cancer 2020)

  Whole-genome and transcriptome sequencing of 570 advanced and metastatic cancers and their matched normals.

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Pan-cancer analysis of whole genomes (ICGC/TCGA, Nature 2020)

  WGS changes cataloged in 2,583 whole-cancer genomes and their matched normal tissues across 38 tumor types. Source data from UCSC Xena (https://xenabrowser.net/datapages/?cohort=PCAWG%20(specimen%20centric)&addHub=htt…

  Multiple or not classified from the titleTCGA (other releases)Source code mixedPubMed 1

• Pan-Cancer MSK-IMPACT MET Validation Cohort (MSK 2022)

  Targeted sequencing of validation samples and their matched normal pairs (except 2samples)via MSK-IMPACT.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• Pediatric European MAPPYACTS Trial (Gustave Roussy, Cancer Discov 2022)

  Whole-exome sequencing of 674 pediatric matched normal samples on multiple pathologies driven on mappyacts program and somatic mutation data for 484 single nucleotide alterations reported as potentially actionable, se…

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Pediatric Pan-cancer (Columbia U, Genome Med 2016)

  Whole exome sequencing of 103 samples (88 with matched normals) from 88 high-risk pediatric cancer patients.

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Pediatric Pan-Cancer (DKFZ, Nature 2017)

  Whole-genome/exome sequencing of 961 Pediatric Cancer samples. Data generated from Pfister Lab & DKFZ/German Cancer Consortium.

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Pediatric Pancan Tumors (MSK,Nat Commun. 2022)

  Targeted NGS of mixed pediatric tumors from MSK-IMPACT testing.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• Pediatric Preclinical Testing Consortium (CHOP, Cell Rep 2019)

  Whole-exome sequencing of 261 patient derived xenografts (PDXs) samples from high-risk childhood cancers (with no matched normals). Website: PPTC (now, PIVOT) (https://preclinicalpivot.org)

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Pediatric solid tumor PDXs (UTHSA, Nat Commun 2023)

  Whole genome and whole exome sequencing of 68 patient-derived xenografts and 65 pediatric patient tumors.

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Solitary Fibrous Tumors (SYSUCC, Nat Commun 2023)

  Targeted sequencing of 131 solitary fibrous tumor samples constituting the SYSUCC discovery cohort.

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• SUMMIT - Neratinib Basket Study (Multi-Institute, Nature 2018)

  MSK-IMPACT sequencing of 86 patients with HER2- and HER3-mutant cancers

  Multiple or not classified from the titleOther published and consortium studiesSource code mixedPubMed 1

• Thoracic Cancer (MSK, Nat Commun 2021)

  Targeted sequencing of tumor and PDX thoracic samples.

  Multiple or not classified from the titleMSK studiesSource code lungPubMed 1

• Thoracic PDX (MSK, Provisional)

  Targeted sequencing of thoracic PDX lines to characterize genetic alterations in 318 tumor/normal pairs via MSK-IMPACT. This cohort is a PDX tracker of all lung cancer PDX generated at MSK that have been through IMPAC…

  Multiple or not classified from the titleMSK studiesSource code lung

• TMB and Immunotherapy (MSK, Nat Genet 2019)

  Genomic and survival data from 1661 tumor-normal pairs from 1661 patients with various cancer types sequenced with the MSK-IMPACT assay.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1

• Tumors with TRK fusions (MSK, Clin Cancer Res 2020)

  Tumors with TRK fusions based on MSK-IMPACT targeted sequencing.

  Multiple or not classified from the titleMSK studiesSource code mixedPubMed 1