This research would not have been possible without the participating patients, their relatives and clinical staff. We are grateful to all of the patients and relatives who took part in this research programme and to the nurses and clinicians in Leeds, Hull, Humber and the East Riding of Yorkshire for their help in recruiting patients to the various components of this research programme.
We are particularly grateful to all of the patient and public involvement representatives involved in this research programme, but specifically Stephen Dixon, Barbara Piggot and Pauline Stabler, who have provided indispensable input across the programme of work.
The contribution of Claire Acey to the co-ordination of all elements of this programme is also gratefully acknowledged.
Finally, we would like to thank the members of the Data Monitoring and Ethics Committee for workstream 4: Peter Vowden, Robert Hinchliffe, Sarah Brown and Christine Gratus.
Contributions of authors
Ian Chetter (Professor, Vascular Surgery) was the chief investigator; led the research programme and chaired the Programme Management Group; and led workstreams 1 and 4.
Catherine Arundel (Research Fellow, Health Research and Trials) contributed to the design, conduct, analysis, interpretation and reporting of workstream 4.
Kerry Bell (Statistician, Health Research and Trials) undertook the statistical analysis and interpretation for workstream 1.
Hannah Buckley (Statistician, Health Research and Trials) undertook the statistical analysis and interpretation and advised on conduct for workstream 1, and advised on the design, conduct and statistical analysis for workstream 4.
Karl Claxton (Professor, Economics) oversaw all aspects of workstream 2 (design, conduct, analysis, interpretation and reporting).
Belen Corbacho Martin (Health Economist, Health Research and Trials) undertook the economic analysis and interpretation for workstream 4.
Nicky Cullum (Professor, Nursing) contributed to the conception, design, conduct, analysis and reporting of all workstreams and provided input to the programme management and strategy.
Jo Dumville (Senior Lecturer, Health Sciences) contributed to the design, conduct, analysis and reporting of all workstreams.
Caroline Fairhurst (Statistician, Health Research and Trials) undertook the statistical analysis for workstream 4.
Eileen Henderson (Assistant to Medical Director, NHS Needs) ensured that all workstreams met NHS needs and were relevant to NHS decision uncertainty.
Karen Lamb (Research Co-ordinator, Wound Research) contributed to the design and conduct of workstream 1 and the design, conduct, analysis and reporting of workstream 4.
Judith Long (Project Manager, Vascular Surgery Research) led and undertook qualitative data collection, analysis and reporting for workstream 4.
Dorothy McCaughan (Research Fellow, Health Research) led and undertook qualitative data collection, analysis and reporting for workstream 3.
Elizabeth McGinnis (Research Fellow, Wound Research) contributed to the design, conduct, analysis and reporting of workstreams 1 and 4.
Angela Oswald (Tissue Viability Matron, Wound Care and Research) provided clinical leadership and expertise in relation to NPWT.
Pedro Saramago Goncalves (Research Fellow, Health Economics) undertook the analyses in workstream 2 and contributed to the design, conduct, interpretation and reporting of workstream 2.
Laura Sheard (Senior Research Fellow, Health Research) undertook qualitative data collection and analysis for workstream 3.
Marta O Soares (Senior Research Fellow, Health Economics) supervised all aspects of workstream 2 (design, conduct, analysis, interpretation and reporting) and contributed to the design, conduct, analysis and reporting of workstreams 1 and 4.
Nikki Stubbs (Clinical Pathway Lead, Wound Research) contributed to the design, conduct, analysis and reporting of workstreams 1 and 4.
David Torgerson (Professor, Health Research and Trials) contributed to the management of the programme of work and the design, conduct, analysis, interpretation and reporting of workstreams 1 and 4.
Nicky Welton (Reader, Statistics and Health Economic Modelling) oversaw the design, interpretation and reporting of the analyses in workstream 2.
Publications
Workstream 1
Chetter C, Oswald A, Fletcher M, Dumville J, Cullum N. A survey of patients with surgical wounds healing by secondary intention; an assessment of prevalence, aetiology, duration and management. J Tissue Viability 2017;26:103–7.
Chetter I, Oswald AV, McGinnis E, Stubbs N, Arundel C, Buckley H, et al. Patients with surgical wounds healing by secondary intention: a prospective, cohort study. Int J Nurs Stud 2019;89:62–71.
Workstream 2
Saramago P, Claxton K, Welton NJ, Soares M. Bayesian econometric modelling of observational data for cost-effectiveness analysis: establishing the value of negative pressure wound therapy in the healing of open surgical wounds. J R Statist Soc A 2020; in press.
Workstream 3
McCaughan D, Sheard L, Dumville J, Cullum N, Chetter I. Patient’s perspectives and experiences of living with a surgical wound healing by secondary intention: an in-depth qualitative study. Int J Nurs Stud 2018;77:29–38.
McCaughan D, Sheard L, Dumville J, Cullum N. Nurses’ and surgeons’ views and experiences of surgical wounds healing by secondary intention: a qualitative study. J Clin Nurs 2020;29:2557–71.
Workstream 4
Arundel C, Buckley H, Clarke E, Cullum N, Dixon S, Dumville J, et al. Negative pressure wound therapy versus usual care for surgical wounds healing by secondary intention (SWHSI trial): study protocol for a randomised controlled pilot trial. Trials 2016;17:535.
Arundel C, Fairhurst C, Corbacho-Martin B, Buckley H, Clarke E, Cullum N, et al. Pilot, feasibility randomized clinical trial of negative pressure wound therapy versus usual care in patients with surgical wounds healing by secondary intention. BJS Open 2018;2:99–111.
Long J, Meethan K, Arundel C, Clarke E, Firth A, Sylvester M, Chetter I. Exploring feedback from research nurses in relation to the design and conduct of a randomised controlled trial of wound care treatments: a sequential, dependent, mixed-methods study. J Tissue Viability 2020; in press.
Data-sharing statement
All data requests should be submitted to the corresponding author for consideration. Access to anonymised data may be granted following review.
Patient data
This work uses data provided by patients and collected by the NHS as part of their care and support. Using patient data is vital to improve health and care for everyone. There is huge potential to make better use of information from people’s patient records, to understand more about disease, develop new treatments, monitor safety, and plan NHS services. Patient data should be kept safe and secure, to protect everyone’s privacy, and it’s important that there are safeguards to make sure that it is stored and used responsibly. Everyone should be able to find out about how patient data are used. #datasaveslives You can find out more about the background to this citation here: https://understandingpatientdata.org.uk/data-citation.
Disclaimers
This report presents independent research funded by the National Institute for Health Research (NIHR). The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, CCF, NETSCC, PGfAR or the Department of Health and Social Care. If there are verbatim quotations included in this publication the views and opinions expressed by the interviewees are those of the interviewees and do not necessarily reflect those of the authors, those of the NHS, the NIHR, NETSCC, the PGfAR programme or the Department of Health and Social Care.