- Macfarlane GJ, Kronisch C, Dean LE, Atzeni F, Häuser W, Fluß E, et al. EULAR revised recommendations for the management of fibromyalgia. Ann Rheum Dis 2017;76:318–28.27377815
- Royal College of Physicians. The Diagnosis of Fibromyalgia Syndrome: UK Clinical Guidelines. London: Royal College of Physicians; 2022. URL: www.rcplondon.ac.uk/file/45391/download (accessed 25 March 2023).
- Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Häuser W, Katz RL, et al. 2016 Revisions to the 2010/2011 fibromyalgia diagnostic criteria. Semin Arthritis Rheum 2016;46:319–29.27916278
- Arnold LM, Bennett RM, Crofford LJ, Dean LE, Clauw DJ, Goldenberg DL, et al. AAPT diagnostic criteria for fibromyalgia. J Pain 2019;20:611–28.30453109
- Hoffman DL, Dukes EM. The health status burden of people with fibromyalgia: a review of studies that assessed health status with the SF-36 or the SF-12. Int J Clin Pract 2008;62:115–26.18039330
- Hughes G, Martinez C, Myon E, Taieb C, Wessely S. The impact of a diagnosis of fibromyalgia on health care resource use by primary care patients in the UK: an observational study based on clinical practice. Arthritis Rheum 2006;54:177–83.16385513
- Mease PJ, Arnold LM, Crofford LJ, Williams DA, Russell IJ, Humphrey L, et al. Identifying the clinical domains of fibromyalgia: contributions from clinician and patient Delphi exercises. Arthritis Rheum 2008;59:952–60.18576290
- Boomershine CS. A comprehensive evaluation of standardized assessment tools in the diagnosis of fibromyalgia and in the assessment of fibromyalgia severity. Pain Res Treat 2012;2012:653714.22110942
- Wu YL, Chang LY, Lee HC, Fang SC, Tsai PS. Sleep disturbances in fibromyalgia: a meta-analysis of case-control studies. J Psychosom Res 2017;96:89–97.28545798
- Haack M, Simpson N, Sethna N, Kaur S, Mullington J. Sleep deficiency and chronic pain: potential underlying mechanisms and clinical implications. Neuropsychopharmacology 2020;45:205–16.31207606
- Theadom A, Cropley M, Humphrey KL. Exploring the role of sleep and coping in quality of life in fibromyalgia. J Psychosom Res 2007;62:145–51.17270572
- Civelek GM, Ciftkaya PO, Karatas M. Evaluation of restless legs syndrome in fibromyalgia syndrome: an analysis of quality of sleep and life. J Back Musculoskelet Rehabil 2014;27:537–44.24867908
- Welsh G, Vincent A, Loehrer L, Cha S, Wahner-Roedler D. Obstructive sleep apnea in patients with fibromyalgia – report from a fibromyalgia clinic. J Sleep Res 2014;23:145.
- Queiroz LP. Worldwide epidemiology of fibromyalgia. Curr Pain Headache Rep 2013;17:356.23801009
- Jones GT, Atzeni F, Beasley M, Flüß E, Sarzi-Puttini P, Macfarlane GJ. The prevalence of fibromyalgia in the general population: a comparison of the American College of Rheumatology 1990, 2010, and modified 2010 classification criteria. Arthritis Rheumatol 2015;67:568–75.25323744
- Wolfe F, Hawley DJ, Wilson K. The prevalence and meaning of fatigue in rheumatic disease. J Rheumatol 1996;23:1407–17.8856621
- Walitt B, Fitzcharles MA, Hassett AL, Katz RS, Häuser W, Wolfe F. The longitudinal outcome of fibromyalgia: a study of 1555 patients. J Rheumatol 2011;38:2238–46.21765102
- Everitt H, Baldwin DS, Stuart B, Lipinska G, Mayers A, Malizia AL, et al. Antidepressants for insomnia in adults. Cochrane Database Syst Rev 2018;5:CD010753.29761479
- Huang CJ, Huang CL, Fan YC, Chen TY, Tsai PS. Insomnia increases symptom severity and health care utilization in patients with fibromyalgia: a population-based study. Clin J Pain 2019;35:780–5.31268891
- Tang NKY, Stella MT, Banks PDW, Sandhu HK, Berna C. The effect of opioid therapy on sleep quality in patients with chronic non-malignant pain: a systematic review and exploratory meta-analysis. Sleep Med Rev 2019;45:105–26.31085434
- National Institute for Health and Care Excellence (NICE). Chronic Pain in Over 16s: Assessment and Management: Draft for Consultation, August 2020. London; Manchester: NICE; 2020. URL: www.nice.org.uk/guidance/ng193/documents/draft-guideline (accessed 14 October 2022).
- Lumley MA, Schubiner H, Lockhart NA, Kidwell KM, Harte SE, Clauw DJ, Williams DA. Emotional awareness and expression therapy, cognitive behavioral therapy, and education for fibromyalgia: a cluster-randomized controlled trial. Pain 2017;158:2354–63.28796118
- McCrae CS, Williams J, Roditi D, Anderson R, Mundt JM, Miller MB, et al. Cognitive behavioral treatments for insomnia and pain in adults with comorbid chronic insomnia and fibromyalgia: clinical outcomes from the SPIN randomized controlled trial. Sleep 2019;42:1–15.
- James Lind Alliance. Fibromyalgia (Canada) Top 10. 2016. URL: www.jla.nihr.ac.uk/priority-setting-partnerships/fibromyalgia-canada/top-10-priorities.htm (accessed 14 October 2022).
- Liedberg GM, Bjork M, Borsbo B. Self-reported nonrestorative sleep in fibromyalgia – relationship to impairments of body functions, personal function factors, and quality of life. J Pain Res 2015;8:499–505.26300656
- Campbell P, Tang N, McBeth J, Lewis M, Main CJ, Croft PR, et al. The role of sleep problems in the development of depression in those with persistent pain: a prospective cohort study. Sleep 2013;36:1693–8.24179303
- Gupta A, Silman AJ, Ray D, Morriss R, Dickens C, MacFarlane GJ, et al. The role of psychosocial factors in predicting the onset of chronic widespread pain: results from a prospective population-based study. Rheumatology (Oxford) 2007;46:666–71.17085772
- Wiklund T, Gerdle B, Linton SJ, Dragioti E, Larsson B. Insomnia is a risk factor for spreading of chronic pain: a Swedish longitudinal population study (SwePain). Eur J Pain 2020;24:1348–56.32386443
- Davies KA, Macfarlane GJ, Nicholl BI, Dickens C, Morriss R, Ray D, McBeth J. Restorative sleep predicts the resolution of chronic widespread pain: results from the EPIFUND study. Rheumatology (Oxford) 2008;47:1809–13.18842606
- Tzadok R, Ablin JN. Current and emerging pharmacotherapy for fibromyalgia. Pain Res Manag 2020;2020:6541798.32104521
- Kundakci B, Kaur J, Goh SL, Hall M, Doherty M, Zhang W, Abhishek A. Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomised controlled trials. Pain 2022;163:1432–45.34813518
- Yeh SW, Hong CH, Shih MC, Tam KW, Huang YH, Kuan YC. Low-level laser therapy for fibromyalgia: a systematic review and meta-analysis. Pain Physician 2019;22:241–54.31151332
- Climent-Sanz C, Morera-Amenos G, Bellon F, Pastells-Peiró R, Blanco-Blanco J, Valenzuela-Pascual F, Gea-Sánchez M. Poor sleep quality experience and self-management strategies in fibromyalgia: a qualitative metasynthesis. J Clin Med 2020;9:4000.33321937
- Higgins J, Green S, Thomas J, Chandler J, Cumpston M, Li T, et al. Cochrane Handbook for Systematic Reviews of Interventions Version 6.2. 2021. URL: https://training.cochrane.org/handbook (accessed June 2021).
- Climent-Sanz C, Marco-Mitjavila A, Pastells-Peiro R, Valenzuela-Pascual F, Blanco-Blanco J, Gea-Sanchez M. Patient reported outcome measures of sleep quality in fibromyalgia: a COSMIN systematic review. Int J Environ Res Public Health 2020;17:2992.32357398
- Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 1989;28:193–213.2748771
- Hays R, Stewart A. Sleep measures. In: Stewart A, Ware J, editors. Measuring Functioning and Well-being: The Medical Outcomes Study Approach. Durham, NC: Duke University Press; 1992. pp. 235–59.
- Jenkins CD, Stanton BA, Niemcryk SJ, Rose RM. A scale for the estimation of sleep problems in clinical research. J Clin Epidemiol 1988;41:313–21.3351539
- Kleinman L, Mannix S, Arnold LM, Burbridge C, Howard K, McQuarrie K, et al. Assessment of sleep in patients with fibromyalgia: qualitative development of the fibromyalgia sleep diary. Health Qual Life Outc 2014;12:111.
- Cappelleri JC, Bushmakin AG, McDermott AM, Sadosky AB, Petrie CD, Martin S. Psychometric properties of a single-item scale to assess sleep quality among individuals with fibromyalgia. Health Qual Life Outc 2009;7:54.
- Burckhardt CS, Clark SR, Bennett RM. The fibromyalgia impact questionnaire: development and validation. J Rheumatol 1991;18:728–33.1865419
- Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I: conceptual framework and item selection. Med Care 1992;30:473–83.1593914
- Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ 2019;366:l4898.31462531
- Fu R, Vandermeer B, Shamliyan T, O’Neil M, Yazdi F, Fox SH, et al. Handling Continuous Outcomes in Quantitative Synthesis: Methods Guide for Effectiveness and Comparative Effectiveness Reviews. Rockville, MD: Agency for Healthcare Research and Quality; 2013.
- StataCorp. Stata Statistical Software: Release 17. College Station, TX: StataCorp LLC; 2021.
- Lunn DJ, Thomas A, Best N, Spiegelhalter D. WinBUGS – a Bayesian modelling framework: concepts, structure, and extensibility. Stat Comput 2000;10:325–37.
- Salanti G, Del Giovane C, Chaimani A, Caldwell DM, Higgins JP. Evaluating the quality of evidence from a network meta-analysis. PLOS ONE 2014;9:e99682.24992266
- Brignardello-Petersen R, Bonner A, Alexander PE, Siemieniuk RA, Furukawa TA, Rochwerg B, et al.; GRADE Working Group. Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis. J Clin Epidemiol 2018;93:36–44.29051107
- Cohen J. Statistical Power Analysis for the Behavioral Sciences. New York: Routledge Academic; 1988.
- Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 2021;372:n71.33782057
- Maindet C, Maire A, Vermorel C, Cracowski C, Rolland C, Forestier R, et al. Spa therapy for the treatment of fibromyalgia: an open, randomized multicenter trial. J Pain 2021; 22:940–51.33677113
- Ceca D, Pablos A, Elvira L, Lopez-Hernandez L, Ortega AL. Effectiveness of a self-myofascial conditioning programme on pain, depression, anxiety and sleep quality in people with fibromyalgia. Cuader Psicol Deport 2020;20:147–65.
- Castro-Sánchez AM, Aguilar-Ferrándiz ME, Matarán-Peñarrocha GA, del Mar Sánchez-Joya M, Arroyo-Morales M, Fernández-de-las-Peñas C. Short-term effects of a manual therapy protocol on pain, physical function, quality of sleep, depressive symptoms, and pressure sensitivity in women and men with fibromyalgia syndrome: a randomized controlled trial. Clin J Pain 2014;30:589–97.24281285
- Jiao J, Russell IJ, Wang W, Wang J, Zhao YY, Jiang Q. Ba-Duan-Jin alleviates pain and fibromyalgia-related symptoms in patients with fibromyalgia: results of a randomised controlled trial. Clin Exp Rheumatol 2019;37:953–62.30789154
- Lynch M, Sawynok J, Hiew C, Marcon D. A randomized controlled trial of qigong for fibromyalgia. Arthritis Res Ther 2012;14:R178.22863206
- Munguía-Izquierdo D, Legaz-Arrese A. Assessment of the effects of aquatic therapy on global symptomatology in patients with fibromyalgia syndrome: a randomized controlled trial. Arch Phys Med Rehabil 2008; 89(12):2250–7.19061736
- Lauche R, Spitzer J, Schwahn B, Ostermann T, Bernardy K, Cramer H, et al. Efficacy of cupping therapy in patients with the fibromyalgia syndrome – a randomised placebo controlled trial. Sci Rep 2016;6:37316.27853272
- San Mauro Martin I, Lopez Oliva S, Collado Yurrita L, Sanz Rojo S, Garicano Vilar E. Anti-inflammatory and antioxidant feeding and supplementation may serve as adjuvants in women with fibromyalgia. J Nutr Intermed Metab 2019;15:3–9.
- Barmaki M, Maindet-Dominici C, Nizard J, Baron D, Russ I, Fardellone P, et al. Multicenter, prospective, controlled double-blind study comparing Fib-19-01, a phytotherapy treatment, to a dietary supplement and to conventional care in patients suffering from fibromyalgia. Altern Ther Health Med 2019;25:46–53.
- Amutio A, Franco C, Sanchez-Sanchez LC, Pérez-Fuentes MC, Gázquez-Linares JJ, Van Gordon W, Molero-Jurado MM. Effects of mindfulness training on sleep problems in patients with fibromyalgia. Front Psychol 2018;9:e01365.
- Simister HD, Tkachuk GA, Shay BL, Vincent N, Pear JJ, Skrabek RQ. Randomized controlled trial of online acceptance and commitment therapy for fibromyalgia. J Pain 2018;19:741–53.29481976
- Schmidt S, Grossman P, Schwarzer B, Jena S, Naumann J, Walach H. Treating fibromyalgia with mindfulness-based stress reduction: results from a 3-armed randomized controlled trial. Pain 2011;152:361–9.21146930
- Lami MJ, Martinez MP, Miro E, Sánchez AI, Prados G, Cáliz R, Vlaeyen JWS. Efficacy of combined cognitive-behavioral therapy for insomnia and pain in patients with fibromyalgia: a randomized controlled trial. Cognit Ther Res 2018;42:63–79.
- Onieva-Zafra MD, Parra-Fernandez ML, Fernandez-Martinez E. Benefits of a home treatment program using guided imagery relaxation based on audio recordings for people with fibromyalgia. Holist Nurs Pract 2019;33:111–20.30747780
- Senna MK, Sallam RA, Ashour HS, Elarman M. Effect of weight reduction on the quality of life in obese patients with fibromyalgia syndrome: a randomized controlled trial. Clin Rheumatol 2012;31:1591–7.22948223
- Arcos-Carmona IM, Castro-Sánchez AM, Matarán-Peñarrocha GA, Gutiérrez-Rubio AB, Ramos-González E, Moreno-Lorenzo C. Effects of aerobic exercise program and relaxation techniques on anxiety, quality of sleep, depression, and quality of life in patients with fibromyalgia: a randomized controlled trial. Med Clin (Barc) 2011;137:398–401.21345470
- Castro-Sanchez AM, Mataran-Pearrocha GA, Granero-Molina J, Aguilera-Manrique G, Quesada-Rubio JM, Moreno-Lorenzo C. Benefits of massage-myofascial release therapy on pain, anxiety, quality of sleep, depression, and quality of life in patients with fibromyalgia. Evid Based Complement Alternat Med 2011;2011:561753.21234327
- Nadal-Nicolás Y, Rubio-Arias JA, Martínez-Olcina M, Reche-García C, Hernández-García M, Martínez-Rodríguez A. Effects of manual therapy on fatigue, pain, and psychological aspects in women with fibromyalgia. Int J Environ Res Public Health 2020;17:4611–4.32604939
- Ide MR, Laurindo LMM, Rodrigues-Junior AL, Tanaka C. Effect of aquatic respiratory exercise-based program in patients with fibromyalgia. Int J Rheum Dis 2008;11:131–40.
- Liu W, Zahner L, Cornell M, Le T, Ratner J, Wang Y, et al. Benefit of Qigong exercise in patients with fibromyalgia: a pilot study. Int J Neurosci 2012;122:657–64.22784212
- Sarmento CVM, Moon S, Pfeifer T, Smirnova IV, Colgrove Y, Lai SM, Liu W. The therapeutic efficacy of Qigong exercise on the main symptoms of fibromyalgia: a pilot randomized clinical trial. Integr Med Res 2020;9:100416.32455108
- Guinot M, Maindet C, Hodaj H, Hodaj E, Bachasson D, Baillieul S, et al. Effects of repetitive transcranial magnetic stimulation and multicomponent therapy in patients with fibromyalgia: a randomized controlled trial. Arthrit Care Res 2021;73:449–58.
- Moustafa IM, Diab AA. The addition of upper cervical manipulative therapy in the treatment of patients with fibromyalgia: a randomized controlled trial. Rheumatol Int 2015;35:1163–74.25782585
- Goldway N, Ablin J, Lubin O, Zamir Y, Keynan JN, Or-Borichev A, et al. Volitional limbic neuromodulation exerts a beneficial clinical effect on fibromyalgia. NeuroImage 2019;186:758–70.30408596
- Samartin-Veiga N, Pidal-Miranda M, Gonzalez-Villar AJ, Bradley C, Garcia-Larrea L, O'Brien AT, Carrillo-de-la-Peña MT. Transcranial direct current stimulation of three cortical targets is no more effective than placebo as treatment for fibromyalgia: a double-blind sham-controlled clinical trial. Pain 2021;163:e850–61.34561393
- Wu YL, Fang SC, Chen SC, Tai CJ, Tsai PS. Effects of neurofeedback on fibromyalgia: a randomized controlled trial. Pain Manag Nurs 2021;22:755–63.33579615
- Mirzaei A, Zabihiyeganeh M, Jahed SA, Khiabani E, Nojomi M, Ghaffari S. Effects of vitamin D optimization on quality of life of patients with fibromyalgia: a randomized controlled trial. Med J Islam Repub Iran 2018;32:29.30159280
- Mataran-Penarrocha GA, Castro-Sanchez AM, Garcia GC, Moreno-Lorenzo C, Carreno TP, Zafra MDO. Influence of craniosacral therapy on anxiety, depression and quality of life in patients with fibromyalgia. Evid Based Complement Alternat Med 2011;2011:178769.19729492
- Gómez-Hernández M, Gallego-Izquierdo T, Martínez-Merinero P, Pecos-Martín D, Ferragut-Garcías A, Hita-Contreras F, et al. Benefits of adding stretching to a moderate-intensity aerobic exercise programme in women with fibromyalgia: a randomized controlled trial. Clin Rehabil 2020;34:242–51.31847574
- de Medeiros SA, de Almeida Silva HJ, do Nascimento RM, da Silva Maia JB, de Almeida Lins CA, de Souza MC. Mat Pilates is as effective as aquatic aerobic exercise in treating women with fibromyalgia: a clinical, randomized and blind trial. Adv Rheumatol 2020;60:21.32252822
- Wang C, Schmid CH, Fielding RA, Harvey WF, Reid KF, Price LL, et al. Effect of tai chi versus aerobic exercise for fibromyalgia: comparative effectiveness randomized controlled trial. BMJ 2018;360:k851.29563100
- Kurt EE, Kocak FA, Erdem HR, Tuncay F, Kelez F. Which non-pharmacological treatment is more effective on clinical parameters in patients with fibromyalgia: balneotherapy or aerobic exercise? Arch Rheumatol 2016;31:162–9.29900959
- Jones KD, Sherman CA, Mist SD, Carson JW, Bennett RM, Li F. A randomized controlled trial of 8-form Tai chi improves symptoms and functional mobility in fibromyalgia patients. Clin Rheumatol 2012;31:1205–14.22581278
- Maddali Bongi S, Paoletti G, Calà M, Del Rosso A, El Aoufy K, Mikhaylova S. Efficacy of rehabilitation with Tai Ji Quan in an Italian cohort of patients with fibromyalgia syndrome. Complement Ther Clin Pract 2016;24:109–15.27502810
- Mist S, Jones K, Sherman C, Carson J, Bennett R, Li F. A randomized controlled trial of 8-form Tai chi improves symptoms and functional mobility in fibromyalgia patients. BMC Complement Altern Med 2012;12:e21.
- Fonseca ACS, Faria PC, Alcântara MA, Pinto WD, De Carvalho LG, Lopes FG, Pernambuco AP. Effects of aquatic physiotherapy or health education program in women with fibromyalgia: a randomized clinical trial. Physiother Theory Pract 2021;37:620–32.31305209
- Martínez MP, Miró E, Sánchez AI, Díaz-Piedra C, Cáliz R, Vlaeyen JWS, Buela-Casal G. Cognitive-behavioral therapy for insomnia and sleep hygiene in fibromyalgia: a randomized controlled trial. J Behav Med 2014;37:683–97.23744045
- Miró E, Lupiáñez J, Martínez MP, Sánchez AI, Díaz-Piedra C, Guzmán MA, Buela-Casal G. Cognitive-behavioral therapy for insomnia improves attentional function in fibromyalgia syndrome: a pilot, randomized controlled trial. J Health Psychol 2011;16:770–82.21346020
- Wang C, Schmid CH, Rones R, Kalish R, Yinh J, Goldenberg DL, et al. A randomized trial of tai chi for fibromyalgia. N Engl J Med 2010;363:743–54.20818876
- Molina-Torres G, Rodríguez-Archilla A, Matarán-Peñarrocha G, Albornoz-Cabello M, Aguilar-Ferrándiz ME, Castro-Sánchez AM. Laser therapy and occlusal stabilization splint for temporomandibular disorders in patients with fibromyalgia syndrome: a randomized, clinical trial. Altern Ther Health Med 2016;22:23–31.27622957
- Calandre EP, Rodriguez-Claro ML, Rico-Villademoros F, Vilchez JS, Hidalgo J, Delgado-Rodriguez A. Effects of pool-based exercise in fibromyalgia symptomatology and sleep quality: a prospective randomised comparison between stretching and Ai Chi. Clin Exp Rheumatol 2009;27:S21–8.20074435
- López-Rodríguez MM, Fernández-Martínez M, Matarán-Peñarrocha GA, Rodríguez-Ferrer ME, Granados Gámez G, Aguilar Ferrándiz E. Effectiveness of aquatic biodance on sleep quality, anxiety and other symptoms in patients with fibromyalgia. Med Clin (Barc) 2013;141:471–8.23246170
- Castro Sánchez AM, García López H, Fernández Sánchez M, Pérez Mármol JM, Aguilar-Ferrándiz ME, Luque Suárez A, Matarán Peñarrocha GA. Improvement in clinical outcomes after dry needling versus myofascial release on pain pressure thresholds, quality of life, fatigue, pain intensity, quality of sleep, anxiety, and depression in patients with fibromyalgia syndrome. Disabil Rehabil 2019;41:2235–46.29681188
- Martínez-Rodríguez A, Rubio-Arias J, Ramos-Campo DJ, Reche-García C, Leyva-Vela B, Nadal-Nicolás Y. Psychological and sleep effects of tryptophan and magnesium-enriched Mediterranean diet in women with fibromyalgia. Int J Environ Res Public Health 2020;17:2227.32224987
- Slim M, Calandre EP, Garcia-Leiva JM, Rico-Villademoros F, Molina-Barea R, Rodriguez-Lopez CM, Morillas-Arques P. The effects of a gluten-free diet versus a hypocaloric diet among patients with fibromyalgia experiencing gluten sensitivity-like symptoms. J Clin Gastroenterol 2017;51:500–7.27548732
- Van Gordon W, Shonin E, Dunn TJ, Garcia-Campayo J, Griffiths MD. Meditation awareness training for the treatment of fibromyalgia syndrome: a randomized controlled trial. Br J Health Psychol 2017;22:186–206.27885763
- Prados G, Miro E, Martinez MP, Sanchez AI, Lami MJ, Caliz R. Combined cognitive-behavioral therapy for fibromyalgia: effects on polysomnographic parameters and perceived sleep quality. Int J Clin Health Psychol 2020;20:232–42.32994796
- Ericsson A, Palstam A, Larsson A, Löfgren M, Bileviciute-Ljungar I, Bjersing J, et al. Resistance exercise improves physical fatigue in women with fibromyalgia: a randomized controlled trial. Arthritis Res Ther 2016;18:176.27473164
- Castel A, Fontova R, Montull S, Periñán R, Poveda MJ, Miralles I, et al. Efficacy of a multidisciplinary fibromyalgia treatment adapted for women with low educational levels: a randomized controlled trial. Arthrit Care Res 2013;65:421–31.
- Kong KR, Lee EN. Effects of a cognitive behavior therapy program for patients with fibromyalgia syndrome: a randomized controlled trial. J Korean Acad Nurs 2021;51:347–62.34215712
- Williams DA, Kuper D, Segar M, Mohan N, Sheth M, Clauw DJ. Internet-enhanced management of fibromyalgia: a randomized controlled trial. Pain 2010;151:694–702.20855168
- Racine M, Jensen MP, Harth M, Morley-Forster P, Nielson WR. Operant learning versus energy conservation activity pacing treatments in a sample of patients with fibromyalgia syndrome: a pilot randomized controlled trial. J Pain 2019;20:420–39.30326271
- Castel A, Cascón R, Padrol A, Sala J, Rull M. Multicomponent cognitive-behavioral group therapy with hypnosis for the treatment of fibromyalgia: long-term outcome. J Pain 2012;13:255–65.22285609
- Picard P, Jusseaume C, Boutet M, Dualé C, Mulliez A, Aublet-Cuvellier B. Hypnosis for management of fibromyalgia. Int J Clin Exp Hypn 2013;61:111–23.23153388
- Amirova A, Cropley M, Theadom A. The effectiveness of the Mitchell Method Relaxation Technique for the treatment of fibromyalgia symptoms: a three-arm randomized controlled trial. Int J Stress Manag 2017;24:86–106.
- Nelson DV, Bennett RM, Barkhuizen A, Sexton GJ, Jones KD, Esty ML, et al. Neurotherapy of fibromyalgia? Pain Med 2010;11:912–9.20624243
- Curtis K, Katz J, Djaiani C, O'Leary G, Uehling J, Carroll J, et al. Evaluation of a hyperbaric oxygen therapy intervention in individuals with fibromyalgia. Pain Med 2021;22:1324–32.33594439
- Udina-Cortes C, Fernandez-Carnero J, Romano AA, Cuenca-Zaldívar JN, Villafañe JH, Castro-Marrero J, Alguacil-Diego IM. Effects of neuro-adaptive electrostimulation therapy on pain and disability in fibromyalgia: a prospective, randomized, double-blind study. Medicine (Baltimore) 2020;99:e23785.33371148
- Toprak Celenay S, Mete O, Akan S, Un Yildirim N, Erten S. Comparison of the effects of stabilization exercise plus kinesio taping and stabilization exercise alone on pain and well-being in fibromyalgia. Complement Ther Clin Pract 2020;38:101076.32056812
- Haak T, Scott B. The effect of Qigong on fibromyalgia (FMS): a controlled randomized study. Disabil Rehabil 2008;30:625–33.17852292
- Wong A, Figueroa A, Sanchez-Gonzalez MA, Son WM, Chernykh O, Park SY. Effectiveness of Tai Chi on cardiac autonomic function and symptomatology in women with fibromyalgia: a randomized controlled trial. J Aging Phys Act 2018;26:214–21.28657825
- Haugmark T, Hagen KB, Provan SA, Smedslund G, Zangi HA. Effects of a mindfulness-based and acceptance-based group programme followed by physical activity for patients with fibromyalgia: a randomised controlled trial. BMJ Open 2021;11:e046943.
- Merchant RE, Andre CA, Wise CM. Nutritional supplementation with Chlorella pyrenoidosa for fibromyalgia syndrome: a double-blind, placebo-controlled, crossover study. J Musculoskelet Pain 2001;9:37–54.
- Deluze C, Bosia L, Zirbs A, Chantraine A, Vischer TL. Electroacupuncture in fibromyalgia: results of a controlled trial. BMJ 1992;305:1249–52.1477566
- Maddali Bongi S, Del Rosso A, Di Felice C, Calà M, Giambalvo Dal Ben G. Rességuier method and Qi Gong sequentially integrated in patients with fibromyalgia syndrome. Clin Exp Rheumatol 2012;30:51–8.
- Potvin S, Morin M, Cloutier C, Gendron A, Bissonnette A, Marchand S. Add-on treatment of quetiapine for fibromyalgia: a pilot, randomized, double-blind, placebo-controlled 12-week trial. J Clin Psychopharmacol 2012;32:684–7.22926604
- Di Pierro F, Rossi A, Consensi A, Giacomelli C, Bazzichi L. Role for a water-soluble form of CoQ10 in female subjects affected by fibromyalgia. A preliminary study. Clin Exp Rheumatol 2017;35:20–7.
- Reuter E, Tafelski S, Thieme K, West C, Haase U, Beck L, et al. Treatment of fibromyalgia syndrome with gamma-hydroxybutyrate: a randomized controlled study. Schmerz 2017;31:149–58.27807735
- Calandre EP, Rico-Villademoros F, Galán J, Molina-Barea R, Vilchez JS, Rodriguez-Lopez CM, et al. Quetiapine extended-release (Seroquel-XR) versus amitriptyline monotherapy for treating patients with fibromyalgia: a 16-week, randomized, flexible-dose, open-label trial. Psychopharmacology (Berl) 2014;231:2525–31.24398824
- de Zanette SA, Vercelino R, Laste G, Rozisky JR, Schwertner A, Machado CB, et al. Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia: a phase II, randomized, double-dummy, controlled trial. BMC Pharmacol Toxicol 2014;15:40.25052847
- Arnold LM, Goldenberg DL, Stanford SB, Lalonde JK, Sandhu HS, Keck PE, et al. Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial. Arthritis Rheum 2007;56:1336–44.17393438
- Arnold LM, Arsenault P, Huffman C, Patrick JL, Messig M, Chew ML, et al. Once daily controlled-release pregabalin in the treatment of patients with fibromyalgia: a phase III, double-blind, randomized withdrawal, placebo-controlled study. Curr Med Res Opin 2014;30:2069–83.24867298
- Ohta H, Oka H, Usui C, Ohkura M, Suzuki M, Nishioka K. A randomized, double-blind, multicenter, placebo-controlled phase III trial to evaluate the efficacy and safety of pregabalin in Japanese patients with fibromyalgia. Arthritis Res Ther 2012;14:R217.23062189
- Arnold LM, Russell IJ, Diri EW, Duan WR, Young JP, Sharma U, et al. A 14-week, randomized, double-blinded, placebo-controlled monotherapy trial of pregabalin in patients with fibromyalgia. J Pain 2008;9:792–805.18524684
- Crofford LJ, Rowbotham MC, Mease PJ, Russell IJ, Dworkin RH, Corbin AE, et al.; Pregabalin 1008-105 Study Group. Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2005;52:1264–73.15818684
- Mease PJ, Russell IJ, Arnold LM, Florian H, Young JP, Martin SA, Sharma U. A randomized, double-blind, placebo-controlled, phase III trial of pregabalin in the treatment of patients with fibromyalgia. J Rheumatol 2008;35:502–14.18278830
- Gilron I, Chaparro LE, Tu D, Holden RR, Milev R, Towheed T, et al. Combination of pregabalin with duloxetine for fibromyalgia: a randomized controlled trial. Pain 2016;157:1532–40.26982602
- Boomershine CS, Koch TA, Morris D. A blinded, randomized, placebo-controlled study to investigate the efficacy and safety of ferric carboxymaltose in iron-deficient patients with fibromyalgia. Rheumatol Ther 2018;5:271–81.29149437
- Arnold LM, Chatamra K, Hirsch I, Stoker M. Safety and efficacy of esreboxetine in patients with fibromyalgia: an 8-week, multicenter, randomized, double-blind, placebo-controlled study. Clin Ther 2010;32:1618–32.20974319
- Ahmed M, Aamir R, Jishi Z, Scharf MB. The effects of milnacipran on sleep disturbance in fibromyalgia: a randomized, double-blind, placebo-controlled, two-way crossover study. J Clin Sleep Med 2016;12:79–86.26414990
- Branco JC, Zachrisson O, Perrot S, Mainguy Y; Multinational Coordinator Study Group. A European multicenter randomized double-blind placebo-controlled monotherapy clinical trial of milnacipran in treatment of fibromyalgia. J Rheumatol 2010;37:851–9.20156949
- González-Viejo MA, Avellanet M, Hernández-Morcuende MI. A comparative study of fibromyalgia treatment: ultrasonography and physiotherapy versus sertraline treatment. Ann Readapt Med Phys 2005;48:610–5.15979192
- Moldofsky H, Inhaber NH, Guinta DR, Alvarez-Horine SB. Effects of sodium oxybate on sleep physiology and sleep/wake-related symptoms in patients with fibromyalgia syndrome: a double-blind, randomized, placebo-controlled study. J Rheumatol 2010;37:2156–66.20682669
- Spaeth M, Bennett RM, Benson BA, Wang YG, Lai C, Choy EH. Sodium oxybate therapy provides multidimensional improvement in fibromyalgia: results of an international phase 3 trial. Ann Rheum Dis 2012;71:935–42.22294641
- Russell JI, Holman AJ, Swick TJ, Alvarez-Horine S, Wang GY, Guinta D; Sodium Oxybate 06-008 FM Study Group. Sodium oxybate reduces pain, fatigue, and sleep disturbance and improves functionality in fibromyalgia: results from a 14-week, randomized, double-blind, placebo-controlled study. Pain 2011; 152(5):1007–17.21397402
- Vitton O, Gendreau M, Gendreau J, Kranzler J, Rao SG. A double-blind placebo-controlled trial of milnacipran in the treatment of fibromyalgia. Hum Psychopharmacol 2004;19:S27–35.15378666
- Yeephu S, Suthisisang C, Suttiruksa S, Prateepavanich P, Limampai P, Russell IJ. Efficacy and safety of mirtazapine in fibromyalgia syndrome patients: a randomized placebo-controlled pilot study. Ann Pharmacother 2013;47:921–32.23737510
- Arnold LM, Blauwet MB, Tracy K, Cai N, Walzer M, Blahunka P, Marek GJ. Efficacy and safety of ASP0819 in patients with fibromyalgia: results of a proof-of-concept, randomized, double-blind, placebo-controlled trial. J Pain Res 2020;13:3355–69.33328761
- Pauer L, Winkelmann A, Arsenault P, Jespersen A, Whelan L, Atkinson G, et al.; A0081100 Investigators. An international, randomized, double-blind, placebo-controlled, phase III trial of pregabalin monotherapy in treatment of patients with fibromyalgia. J Rheumatol 2011;38:2643–52.21965636
- Mameli S, Pisanu GM, Sardo S, Marchi A, Pili A, Carboni M, et al. Oxytocin nasal spray in fibromyalgic patients. Rheumatol Int 2014;34:1047–52.24509894
- Deschenes M, Garber C. General principles of exercise prescription. In: Pescatello L, Arena R, Riebe D, Thompson P, editors. ACSM’s Guidelines for Exercise Testing and Prescription. 9th edn. Baltimore, MD: Lippincott Williams & Wilkins; 2013. pp. 162–93.
- Goh SL, Persson MSM, Stocks J, Hou Y, Welton NJ, Lin J, et al. Relative efficacy of different exercises for pain, function, performance and quality of life in knee and hip osteoarthritis: systematic review and network meta-analysis. Sports Med 2019;49:743–61.30830561
- Pagliai G, Colombini B, Dinu M, Whittaker A, Masoni A, Danza G, et al. Effectiveness of a khorasan wheat-based replacement on pain symptoms and quality of life in patients with fibromyalgia. Pain Med 2020;21:2366–72.32488245
- Edwards AM, Blackburn L, Christie S, Townsend S, David J. Food supplements in the treatment of primary fibromyalgia: a double-blind, crossover trial of anthocyanidins and placebo. J Nutr Environ Med 2000;10:189–99.
- Scharf MB, Baumann M, Berkowitz DV. The effects of sodium oxybate on clinical symptoms and sleep patterns in patients with fibromyalgia. J Rheumatol 2003;30:1070–4.12734908
- Arnold LM, Sarzi-Puttini P, Arsenault P, Khan T, Bhadra Brown P, Clair A, et al. Efficacy and safety of pregabalin in patients with fibromyalgia and comorbid depression taking concurrent antidepressant medication: a randomized, placebo-controlled study. J Rheumatol 2015;42:1237–44.26034150
- Roth T, Lankford DA, Bhadra P, Whalen E, Resnick EM. Effect of pregabalin on sleep in patients with fibromyalgia and sleep maintenance disturbance: a randomized, placebo-controlled, 2-way crossover polysomnography study. Arthrit Care Res 2012;64:597–606.
- Roehrs T, Withrow D, Koshorek G, Verkler J, Bazan L, Roth T. Sleep and pain in humans with fibromyalgia and comorbid insomnia: double-blind, crossover study of suvorexant 20 mg versus placebo. J Clin Sleep Med 2020;16:415–21.31992394
- Ware MA, Fitzcharles MA, Joseph L, Shir Y. The effects of nabilone on sleep in fibromyalgia: results of a randomized controlled trial. Anesth Analg 2010;110:604–10.20007734
- Geler Kulcu D, Gulsen G. Effect of physical therapy program on insomnia severity in a patient population with fibromyalgia syndrome. Turk Fiziks Tip Rehabilit Derg 2009;55:64–7.
- Celebi E, Ataoglu S, Bahar Ataoglu B, Ankarali H, Ozsahin M, Pasin O. The investigation effects of pregabalin and duloxetine treatment according to personality characteristics groupe with fibromyalgia patients. Duzce Med J 2016;18:47–53.
- Collazo Chao E, Munoz Reina MD. Scalp acupuncture and acupunture for treatment of patients with fibromyalgia. Prospective randomized study. Revis Intern Acupunt 2013;7:6–11.
- Ammer K, Melnizky P. Medicinal baths for the treatment of generalized fibromyalgia. Forsch Komplementarmed 1999;6:80–5.10352370
- Biasi G, Badii F, Magaldi M, Moltoni L, Marcolongo R. A new approach in the treatment of fibromyalgia: the use of a copper wire sheet (‘Telo Cypro’). Minerva Med 1999;90:39–43.10388462
- Arnold LM, Schikler KN, Bateman L, Khan T, Pauer L, Bhadra-Brown P, et al.; Pregabalin Adolescent Fibromyalgia Study Group. Safety and efficacy of pregabalin in adolescents with fibromyalgia: a randomized, double-blind, placebo-controlled trial and a 6-month open-label extension study. Pediatr Rheumatol Online J 2016;14:46.27475753
- Gür A, Karakoc M, Nas K, Cevik R, Sarac J, Ataoglu S. Effects of low power laser and low dose amitriptyline therapy on clinical symptoms and quality of life in fibromyalgia: a single-blind, placebo-controlled trial. Rheumatol Int 2002;22:188–93.12215864
- McCrae CS, Mundt JM, Curtis AF, Craggs JG, O’Shea AM, Staud R, et al. Gray matter changes following cognitive behavioral therapy for patients with comorbid fibromyalgia and insomnia: a pilot study. J Clin Sleep Med 2018;14:1595–603.30176973
- Arnold LM, Clauw D, Wang F, Ahl J, Gaynor PJ, Wohlreich MM. Flexible dosed duloxetine in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled trial. J Rheumatol 2010;37:2578–86.20843911
- Roizenblatt S, Fregni F, Gimenez R, Wetzel T, Rigonatti SP, Tufik S, et al. Site-specific effects of transcranial direct current stimulation on sleep and pain in fibromyalgia: a randomized, sham-controlled study. Pain Pract 2007;7:297–306.17986164
- Mhalla A, Baudic S, de Andrade DC, Gautron M, Perrot S, Teixeira MJ, et al. Long-term maintenance of the analgesic effects of transcranial magnetic stimulation in fibromyalgia. Pain 2011;152:1478–85.21397400
- Jones KD, Burckhardt CS, Deodhar AA, Perrin NA, Hanson GC, Bennett RM. A six-month randomized controlled trial of exercise and pyridostigmine in the treatment of fibromyalgia. Arthritis Rheum 2008;58:612–22.18240245
- Gür A, Karakoç M, Nas K, Cevik R, Saraç J, Demir E. Efficacy of low power laser therapy in fibromyalgia: a single-blind, placebo-controlled trial. Lasers Med Sci 2002;17:57–61.11845369
- Hargrove JB, Bennett RM, Simons DG, Smith SJ, Nagpal S, Deering DE. A randomized placebo-controlled study of noninvasive cortical electrostimulation in the treatment of fibromyalgia patients. Pain Med 2012;13:115–24.22233397
- Toprak Celenay S, Anaforoglu Kulunkoglu B, Yasa ME, Sahbaz Pirincci C, Un Yildirim N, Kucuksahin O, et al. A comparison of the effects of exercises plus connective tissue massage to exercises alone in women with fibromyalgia syndrome: a randomized controlled trial. Rheumatol Int 2017;37:1799–806.28840379
- Maestú C, Blanco M, Nevado A, Romero J, Rodríguez-Rubio P, Galindo J, et al. Reduction of pain thresholds in fibromyalgia after very low-intensity magnetic stimulation: a double-blinded, randomized placebo-controlled clinical trial. Pain Res Manag 2013;18:e101–6.24308025
- Bircan C, Karasel SA, Akgün B, El O, Alper S. Effects of muscle strengthening versus aerobic exercise program in fibromyalgia. Rheumatol Int 2008;28:527–32.17982749
- Dönmez A, Karagülle MZ, Tercan N, Dinler M, Işsever H, Karagülle M, Turan M. SPA therapy in fibromyalgia: a randomised controlled clinic study. Rheumatol Int 2005;26:168–72.15965635
- Azad KA, Alam MN, Haq SA, Nahar S, Chowdhury MA, Ali SM, Ullah AK. Vegetarian diet in the treatment of fibromyalgia. Bangladesh Med Res Counc Bull 2000;26:41–7.11508070
- Wigers SH, Stiles TC, Vogel PA. Effects of aerobic exercise versus stress management treatment in fibromyalgia. A 4.5 year prospective study. Scand J Rheumatol 1996;25:77–86.8614771
- Häkkinen A, Häkkinen K, Hannonen P, Alen M. Strength training induced adaptations in neuromuscular function of premenopausal women with fibromyalgia: comparison with healthy women. Ann Rheum Dis 2001;60:21–6.11114277
- Rossini M, Di Munno O, Valentini G, Bianchi G, Biasi G, Cacace E, et al. Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients. Clin Exp Rheumatol 2007;25:182–8.17543140
- Gillis ME, Lumley MA, Mosley-Williams A, Leisen JC, Roehrs T. The health effects of at-home written emotional disclosure in fibromyalgia: a randomized trial. Ann Behav Med 2006;32:135–46.16972811
- Saral I, Sindel D, Esmaeilzadeh S, Sertel-Berk HO, Oral A. The effects of long- and short-term interdisciplinary treatment approaches in women with fibromyalgia: a randomized controlled trial. Rheumatol Int 2016;36:1379–89.27055444
- Buskila D, Abu-Shakra M, Neumann L, Odes L, Shneider E, Flusser D, Sukenik S. Balneotherapy for fibromyalgia at the Dead Sea. Rheumatol Int 2001;20:105–8.11354556
- Pujol J, Ramos-López D, Blanco-Hinojo L, Pujol G, Ortiz H, Martínez-Vilavella G, et al. Testing the effects of gentle vibrotactile stimulation on symptom relief in fibromyalgia. Arthritis Res Ther 2019;21:148.31200775
- Braz AS, Morais LC, Paula AP, Diniz MF, Almeida RN. Effects of Panax ginseng extract in patients with fibromyalgia: a 12-week, randomized, double-blind, placebo-controlled trial. Braz J Psychiatry 2013;35:21–8.23567596
- Maddali Bongi S, Di Felice C, Del Rosso A, Galluccio F, Landi G, Tai G, et al. The efficacy of the Resseguier method in the treatment of fibromyalgia syndrome: a randomised controlled trial. Clin Exp Rheumatol 2010;28:S46–50.
- Colbert AP, Markov MS, Banerji M, Pilla AA. Magnetic mattress pad use in patients with fibromyalgia: a randomized double-blind pilot study. J Back Musculosk Rehab 1999;13:19–31.
- Sanudo B, Carrasco L, de Hoyo M, Figueroa A, Saxton JM. Vagal modulation and symptomatology following a 6-month aerobic exercise programme for women with fibromyalgia. Clin Exp Rheumatol 2015;33:S41–5.25786042
- Lichtbroun AS, Raicer MM, Smith RB. The treatment of fibromyalgia with cranial electrotherapy stimulation. J Clin Rheumatol 2001;7:72–8; discussion 78.17039098
- Norregaard J, Lykkegaard JJ, Mehlsen J, DanneskioldSamsoe B. Exercise training in treatment of fibromyalgia. J Musculoskelet Pain 1997;5:71–9.
- Genc A, Tur BS, Aytur YK, Oztuna D, Erdogan MF. Does aerobic exercise affect the hypothalamic-pituitary-adrenal hormonal response in patients with fibromyalgia syndrome? J Phys Ther Sci 2015;27:2225–31.26311959
- Darnall BD, Krishnamurthy P, Tsuei J, Minor JD. Self-administered skills-based virtual reality intervention for chronic pain: randomized controlled pilot study. JMIR Form Res 2020;4:e17293.32374272
- Ceballos-Laita L, Mingo-Gomez MT, Estebanez-de-Miguel E, Bueno-Gracia E, Navas-Cámara FJ, Verde-Rello Z, et al. Does the addition of pain neurophysiology education to a therapeutic exercise program improve physical function in women with fibromyalgia syndrome? Secondary analysis of a randomized controlled trial. J Clin Med 2021;10:2518.34200137
- Sadreddini S, Molaeefard M, Noshad H, Ardalan M, Asadi A. Efficacy of Raloxifen in treatment of fibromyalgia in menopausal women. Eur J Intern Med 2008;19:350–5.18549938
- Younger J, Noor N, McCue R, Mackey S. Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels. Arthritis Rheum 2013;65:529–38.23359310
- Edinger JD, Wohlgemuth WK, Krystal AD, Rice JR. Behavioral insomnia therapy for fibromyalgia patients: a randomized clinical trial. Arch Intern Med 2005;165:2527–35.16314551
- Almeida TF, Roizenblatt S, Benedito-Silva AA, Tufik S. The effect of combined therapy (ultrasound and interferential current) on pain and sleep in fibromyalgia. Pain 2003;104:665–72.12927639
- Moretti FA, Marcondes FB, Provenza JR, Fukuda TY, de Vasconcelos RA, Roizenblatt S. Combined therapy (ultrasound and interferential current) in patients with fibromyalgia: once or twice in a week? Physiother Res Int 2012;17:142–9.22114059
- Taylor AG, Anderson JG, Riedel SL, Lewis JE, Kinser PA, Bourguignon C. Cranial electrical stimulation improves symptoms and functional status in individuals with fibromyalgia. Pain Manag Nurs 2013;14:327–35.24315255
- Lauretti GR, Chubaci EF, Mattos AL. Efficacy of the use of two simultaneously TENS devices for fibromyalgia pain. Rheumatol Int 2013;33:2117–22.23423539
- Cash E, Salmon P, Weissbecker I, Rebholz WN, Bayley-Veloso R, Zimmaro LA, et al. Mindfulness meditation alleviates fibromyalgia symptoms in women: results of a randomized clinical trial. Ann Behav Med 2015;49:319–30.25425224
- da Silva MM, Albertini R, de Tarso Camillo de Carvalho P, Leal-Junior ECP, Bussadori SK, Vieira SS, et al. Randomized, blinded, controlled trial on effectiveness of photobiomodulation therapy and exercise training in the fibromyalgia treatment. Lasers Med Sci 2018;33:343–51.29170901
- Bourgault P, Lacasse A, Marchand S, Courtemanche-Harel R, Charest J, Gaumond I, et al. Multicomponent interdisciplinary group intervention for self-management of fibromyalgia: a mixed-methods randomized controlled trial. PLOS ONE 2015;10:e0126324.25978402
- Hedman-Lagerlöf M, Hedman-Lagerlöf E, Axelsson E, Ljótsson B, Engelbrektsson J, Hultkrantz S, et al. Internet-delivered exposure therapy for fibromyalgia: a randomized controlled trial. Clin J Pain 2018;34:532–42.29077623
- Alves CR, Santiago BM, Lima FR, Otaduy MCG, Calich AL, Tritto ACC, et al. Creatine supplementation in fibromyalgia: a randomized, double-blind, placebo-controlled trial. Arthrit Care Res 2013;65:1449–59.
- Takiguchi RS, Fukuhara VS, Sauer JF, Assumpção A, Marques AP. Effect of acupuncture on pain, sleep and quality of life improvement in fibromyalgia patients: preliminary study. Fisioterap Pesq 2008;15:280–4.
- Aldaoseri HA, Zubairi MB. Vitamin D deficiency and treatment in Iraqi patients with primary fibromyalgia syndrome. Egypt Rheumatol 2019;42:57–50.
- Correia Moretti E, Malta Varela de Araújo ME, Guerra Campos A, de Holanda Santos LR, Rodrigues de Araújo MDG, da Silva Tenório A. Effects of pompage associated with aerobic exercises on pain, fatigue, and sleep quality in female patients with fibromyalgia: a pilot study. Fisioterap Pesq 2016;23:227–33.
- Soares JJF, Grossi G. A randomized, controlled comparison of educational and behavioural interventions for women with fibromyalgia. Scand J Occup Ther 2002;9:35–45.
- Rickardsson J, Gentili C, Andersson E, Zetterqvist V, Andersson E, Persson J, et al. Internet-delivered acceptance and commitment therapy as microlearning for chronic pain: a randomized controlled trial with 1-year follow-up. Eur J Pain 2021;25:1012–30.33460240
- Calandre EP, Hidalgo-Tallon J, Molina-Barea R, Rico-Villademoros F, Molina-Hidalgo C, Garcia-Leiva JM, et al. The probiotic VSL#3 R does not seem to be efficacious for the treatment of gastrointestinal symptomatology of patients with fibromyalgia: a randomized, double-blind, placebo-controlled clinical trial. Pharmaceuticals (Basel) 2021;14:1063.34681287
- Abdel Fattah YH, Elnemr R. Efficacy of pregabalin as a monotherapy versus combined pregabalin and milnacipran in the management of fibromyalgia. Int J Rheum Dis 2020;23(11):1474–80.32886447
- Capaci K, Hepguler S. Comparison of the effects of amitriptyline and paroxetine in the treatment of fibromyalgia syndrome. Pain Clin 2002;14:223–8.
- Montesó-Curto P, García-Martínez M, Gómez-Martínez C, Ferré-Almo S, Panisello-Chavarria ML, Genís SR, et al. Effectiveness of three types of interventions in patients with fibromyalgia in a region of southern Catalonia. Pain Manag Nurs 2015;16:642–52.26104223
- Ramzy EA. Comparative efficacy of newer antidepressants in combination with pregabalin for fibromyalgia syndrome: a controlled, randomized study. Pain Pract 2017;17:32–40.26892006
- Zhang X, Xu H, Zhang Z, Li Y, Pauer L, Liao S, Zhang F. Efficacy and safety of pregabalin for fibromyalgia in a population of Chinese subjects. J Pain Res 2021;14:537–48.33658841
- Salaffi F, Ciapetti A, Gasparini S, Atzeni F, Sarzi-Puttini P, Baroni M. Web/Internet-based telemonitoring of a randomized controlled trial evaluating the time-integrated effects of a 24-week multicomponent intervention on key health outcomes in patients with fibromyalgia. Clin Exp Rheumatol 2015;33:S93–101.25786050
- Fernández García R, Suárez Holgado JD, Formieles Ortiz I, Zurita Ortega F, Valverde Cepeda M, Fernández Sánchez M. Using a laser based program in patients diagnosed with fibromyalgia. Reumatol Clin (Engl Ed) 2011;7:94–7.
- Martin DP, Sletten CD, Williams BA, Berger IH. Improvement in fibromyalgia symptoms with acupuncture: results of a randomized controlled trial. Mayo Clin Proc 2006;81:749–57.16770975
- Kravitz HM, Esty ML, Katz RS, Fawcett J. Treatment of fibromyalgia syndrome using low-intensity neurofeedback with the flexyx neurotherapy system: a randomized controlled clinical trial. J Neurother 2006;10:41–58.
- Altan L, Bingöl U, Aykaç M, Koç Z, Yurtkuran M. Investigation of the effects of pool-based exercise on fibromyalgia syndrome. Rheumatol Int 2004;24:272–7.14508601
- Acet G, Kaya A, Akturk S, Akgol G. A comparison of the effectiveness of amitriptilin and pregabalin treatment in fibromyalgia patients. North Clin Istanb 2017;4:151–9.28971173
- Anderberg UM, Marteinsdottir I, Von Knorring L. Citalopram in patients with fibromyalgia – a randomized, double-blind, placebo-controlled study. Eur J Pain 2000;4:27–35.10833553
- Arnold LM, Rosen A, Pritchett YL, D'Souza DN, Goldstein DJ, Iyengar S, Wernicke JF. A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder. Pain 2005;119:5–15.16298061
- Distler O, Eich W, Dokoupilova E, Dvorak Z, Fleck M, Gaubitz M, et al. Evaluation of the efficacy and safety of terguride in patients with fibromyalgia syndrome: results of a twelve-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Arthritis Rheum 2010;62:291–300.20039417
- Vitorino DF, Carvalho LB, Prado GF. Hydrotherapy and conventional physiotherapy improve total sleep time and quality of life of fibromyalgia patients: randomized clinical trial. Sleep Med 2006;7:293–6.16564209
- Field T, Diego M, Cullen C, Hernandez-Reif M, Sunshine W, Douglas S. Fibromyalgia pain and substance P decrease and sleep improves after massage therapy. J Clin Rheumatol 2002;8:72–6.17041326
- Sanchez AI, Diaz-Piedra C, Miro E, Martinez MP, Galvez R, Buela-Casal G. Effects of cognitive-behavioral therapy for insomnia on polisomnographic parameters in fibromyalgia patients. Int J Clin Health Psychol 2012;12:39–53.
- Hudson J, Imamura M, Robertson C, Whibley D, Aucott L, Gillies K, et al. Effects of pharmacologic and nonpharmacologic interventions for the management of sleep problems in people with fibromyalgia: systematic review and network meta-analysis of randomized controlled trials [published online ahead of print February 10 2025]. Arthritis Care Res 2025. 10.1002/acr.25505
- Ajeesh PS, Sharan D, Rameshkumar R. Prevalence, regional distribution and risk factors of musculoskeletal disorders in caregivers of children with cerebral palsy following multilevel surgery. 6th World Congress of Biomechanics (WCB 2010); 2010 August 1–6; Biomed Engn Soc Singapore, Singapore; 2010.
- Naranjo-Cinto F, Cerón-Cordero AI, Figueroa-Padilla C, Galindo-Paz D, Fernández-Carnero S, Gallego-Izquierdo T, et al. Real versus sham manual therapy in addition to therapeutic exercise in the treatment of non-specific shoulder pain: a randomized controlled trial. J Clin Med 2022;11:4395.35956009
- McCaskey MA, Wirth B, Schuster-Amft C, de Bruin ED. Postural sensorimotor training versus sham exercise in physiotherapy of patients with chronic non-specific low back pain: an exploratory randomised controlled trial. PLOS ONE 2018;13:e0193358.29522571
- Hohenschurz-Schmidt D, Vase L, Scott W, Annoni M, Ajayi OK, Barth J, et al. Recommendations for the development, implementation, and reporting of control interventions in efficacy and mechanistic trials of physical, psychological, and self-management therapies: the CoPPS Statement. BMJ 2023;381:e072108.37230508
- Busch AJ, Barber KA, Overend TJ, Peloso PM, Schachter CL. Exercise for treating fibromyalgia syndrome. Cochrane Database Syst Rev 2007;2007:CD003786.
- Bidonde J, Busch AJ, Schachter CL, Overend TJ, Kim SY, Góes SM, et al. Aerobic exercise training for adults with fibromyalgia. Cochrane Database Syst Rev 2017;6:CD012700.28636204
- Bidonde J, Busch AJ, Webber SC, Schachter CL, Danyliw A, Overend TJ, et al. Aquatic exercise training for fibromyalgia. Cochrane Database Syst Rev 2014;2014:CD011336.25350761
- Langhorst J, Klose P, Dobos GJ, Bernardy K, Hauser W. Efficacy and safety of meditative movement therapies in fibromyalgia syndrome: a systematic review and meta-analysis of randomized controlled trials. Rheumatol Int 2013;33:193–207.22350253
- Bearman M, Dawson P. Qualitative synthesis and systematic review in health professions education. Med Educ 2013;47:252–60.23398011
- Flemming K, Booth A, Garside R, Tunçalp O, Noyes J. Qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods. BMJ Glob Health 2019;4:e000882.
- Barry MJ, Edgman-Levitan S. Shared decision making – pinnacle of patient-centered care. N Engl J Med 2012;366:780–1.22375967
- Lewin S, Booth A, Glenton C, Munthe-Kaas H, Rashidian A, Wainwright M, et al. Applying GRADE-CERQual to qualitative evidence synthesis findings: introduction to the series. Implement Sci 2018;13:2.29384079
- McGowan J, Sampson M, Salzwedel DM, Cogo E, Foerster V, Lefebvre C. PRESS peer review of electronic search strategies: 2015 guideline statement. J Clin Epidemiol 2016;75:40–6.27005575
- France EF, Wells M, Lang H, Williams B. Why, when and how to update a meta-ethnography qualitative synthesis. Syst Rev 2016;5:44.26979748
- The University of California, San Francisco School of Nursing Symptom Management Faculty Group. A model for symptom management. Image J Nurs Sch 1994;26:272–6.7829111
- Dodd M, Janson S, Facione N, Faucett J, Froelicher ES, Humphreys J, et al. Advancing the science of symptom management. J Adv Nurs 2001;33:668–76.11298204
- Critical Appraisal Skills Programme. Qualitative Checklist. Oxford: CASP-UK; 2018. URL: https://casp-uk.net/images/checklist/documents/CASP-Qualitative-Studies-Checklist/CASP-Qualitative-Checklist-2018_fillable_form.pdf (accessed 25 October 2022).
- GRADE-CERQual. Confidence in the Evidence from Reviews of Qualitative Research. 2018. URL: www.cerqual.org/ (accessed 16 February 2023).
- Wentz KAH, Lindberg C, Hallberg LRM. On parole: the natural history of recovery from fibromyalgia in women: a grounded theory study. J Pain Manag 2012;5:177–94.
- Sawynok J, Lynch M, Marcon D. Extension trial of Qigong for fibromyalgia: a quantitative and qualitative study. Evid Based Complement Alternat Med 2013;2013:726062.24069054
- Sawynok J, Lynch M. Qualitative analysis of a controlled trial of qigong for fibromyalgia: advancing understanding of an emerging health practice. J Altern Complement Med 2014;20:606–17.25072523
- Teo M, Mohan B, Oelke ND. Developing and implementing a community-based model of care for fibromyalgia: a feasibility study. Pain Res Manag 2017;2017:4521389.28790879
- Lazaridou A, Koulouris A, Dorado K, Chai P, Edwards RR, Schreiber KL. The impact of a daily yoga program for women with fibromyalgia. Int J Yoga 2019;12:206–17.31543629
- Curry L, Pike M, Lynch M, Marcon D, Sawynok J. Observational study of Qigong as a complementary self-care practice at a tertiary-care pain management unit. Evid Based Complement Alternat Med 2021;2021:6621069.34239585
- Climent-Sanz C, Gea-Sanchez M, Fernandez-Lago H, Mateos-Garcia JT, Rubi-Carnacea F, Briones-Vozmediano E. Sleeping is a nightmare: a qualitative study on the experience and management of poor sleep quality in women with fibromyalgia. J Adv Nurs 2021;77:4549–62.34268797
- Colas C, Jumel A, Vericel MP, Barth N, Manzanares J, Goutte J, et al. Understanding experiences of fibromyalgia patients involved in the Fimouv study during COVID-19 lockdown. Front Psychol 2021;12:645092.34354626
- Pearson J, Whale K, Walsh NE, Derham S, Russell J, Cramp F. Fibromyalgia self‐management: mapping the behaviour change techniques used in a practice‐based programme. Musculoskeletal Care 2020;18:372–82.32452615
- Raymond MC, Brown JB. Experience of fibromyalgia. Qualitative study. Can Fam Physician 2000;46:1100–6.10845136
- Russell D, Álvarez Gallardo IC, Wilson I, Hughes CM, Davison GW, Sañudo B, McVeigh JG. ‘Exercise to me is a scary word’: perceptions of fatigue, sleep dysfunction, and exercise in people with fibromyalgia syndrome – a focus group study. Rheumatol Int 2018;38:507–15.29340774
- Crooks VA. Exploring the altered daily geographies and lifeworlds of women living with fibromyalgia syndrome: a mixed-method approach. Soc Sci Med 2007;64:577–88.17079063
- Cunningham MM, Jillings C. Individuals’ descriptions of living with fibromyalgia. Clin Nurs Res 2006;15:258–73.17056769
- Sturge-Jacobs M. The experience of living with fibromyalgia: confronting an invisible disability. Res Theory Nurs Pract 2002;16:19–31.12371466
- Arnold LM, Crofford LJ, Mease PJ, Burgess SM, Palmer SC, Abetz L, Martin SA. Patient perspectives on the impact of fibromyalgia. Patient Educ Couns 2008;73:114–20.18640807
- Cudney SA, Butler MR, Weinert C, Sullivan T. Ten rural women living with fibromyalgia tell it like it is. Holist Nurs Pract 2002;16:35–45.11913226
- Kengen Traska T, Rutledge DN, Mouttapa M, Weiss J, Aquino J. Strategies used for managing symptoms by women with fibromyalgia. J Clin Nurs 2012;21:626–35.21323780
- Martin S, Chandran A, Zografos L, Zlateva G. Evaluation of the impact of fibromyalgia on patients’ sleep and the content validity of two sleep scales. Health Qual Life Outc 2009;7:64.
- Vincent A, Whipple MO, McAllister SJ, Aleman KM, St Sauver JL. A cross-sectional assessment of the prevalence of multiple chronic conditions and medication use in a sample of community-dwelling adults with fibromyalgia in Olmsted County, Minnesota. BMJ Open 2015;5:e006681.
- Lempp HK, Hatch SL, Carville SF, Choy EH. Patients’ experiences of living with and receiving treatment for fibromyalgia syndrome: a qualitative study. BMC Musculoskelet Disord 2009;10:124.19811630
- Ramlee F, Afolalu EF, Tang NKY. Do people with chronic pain judge their sleep differently? A qualitative study. Behav Sleep Med 2018;16:259–71.27337439
- Theadom A, Cropley M. ‘This constant being woken up is the worst thing’ – experiences of sleep in fibromyalgia syndrome. Disabil Rehabil 2010;32:1939–47.20919892
- Söderberg S, Lundman B, Norberg A. The meaning of fatigue and tiredness as narrated by women with fibromyalgia and healthy women. J Clin Nurs 2002;11:247–55.11903724
- Sallinen M, Kukkurainen ML, Peltokallio L, Mikkelsson M. ‘I’m tired of being tired’ – fatigue as experienced by women with fibromyalgia. Adv Physiother 2011;13:11–7.
- Humphrey L, Arbuckle R, Mease P, Williams DA, Samsoe BD, Gilbert C. Fatigue in fibromyalgia: a conceptual model informed by patient interviews. BMC Musculoskelet Disord 2010;11:216.20854680
- Vincent A, Whipple MO, Rhudy LM. Fibromyalgia flares: a qualitative analysis. Pain Med 2016;17:463–8.25586303
- Goelema MS, Regis M, Haakma R, van den Heuvel ER, Markopoulos P, Overeem S. Determinants of perceived sleep quality in normal sleepers. Behav Sleep Med 2019;17:388–97.28929803
- Klein PJ, Baumgarden J, Schneider R. Qigong and Tai Chi as therapeutic exercise: survey of systematic reviews and meta-analyses addressing physical health conditions. Altern Ther Health Med 2019;25:48–53.31221939
- Finan PH, Goodin BR, Smith MT. The association of sleep and pain: an update and a path forward. J Pain 2013;14:1539–52.24290442
- Whibley D, AlKandari N, Kristensen K, Barnish M, Rzewuska M, Druce KL, Tang NKY. Sleep and pain: a systematic review of studies of mediation. Clin J Pain 2019;35:544–58.30829737
- Finan PH, Smith MT. The comorbidity of insomnia, chronic pain, and depression: dopamine as a putative mechanism. Sleep Med Rev 2013;17:173–83.22748562
- Smith MT, Perlis ML, Carmody TP, Smith MS, Giles DE. Presleep cognitions in patients with insomnia secondary to chronic pain. J Behav Med 2001;24:93–114.11296472
- Grandner MA, Jackson NJ, Izci-Balserak B, Gallagher RA, Murray-Bachmann R, Williams NJ, et al. Social and behavioral determinants of perceived insufficient sleep. Front Neurol 2015;6:112.26097464
- Brooks Holliday S, Dubowitz T, Ghosh-Dastidar B, Beckman R, Buysse D, Hale L, et al. Do sleep and psychological distress mediate the association between neighborhood factors and pain? Pain Med 2019;20:278–89.29767771
- Theadom A, Cropley M. Dysfunctional beliefs, stress and sleep disturbance in fibromyalgia. Sleep Med 2008;9:376–81.17681881
- Shaver JL, Woods NF. Sleep and menopause: a narrative review. Menopause 2015;22:899–915.26154276
- Freedman RR, Roehrs TA. Sleep disturbance in menopause. Menopause 2007;14:826–9.17486023
- Eichling PS, Sahni J. Menopause related sleep disorders. J Clin Sleep Med 2005;1:291–300.17566192
- Black N. Patient reported outcome measures could help transform healthcare. BMJ 2013;346:f167.23358487
- McNair AG, Whistance RN, Forsythe RO, Rees J, Jones JE, Pullyblank AM, et al. Synthesis and summary of patient-reported outcome measures to inform the development of a core outcome set in colorectal cancer surgery. Colorectal Dis 2015;17:217–29.
- Macefield RC, Jacobs M, Korfage IJ, Nicklin J, Whistance RN, Brookes ST, et al. Developing core outcomes sets: methods for identifying and including patient-reported outcomes (PROs). Trials 2014;15:49.24495582
- Prinsen CAC, Mokkink LB, Bouter LM, Alonso J, Patrick DL, de Vet HCW, Terwee CB. COSMIN guideline for systematic reviews of patient-reported outcome measures. Qual Life Res 2018;27:1147–57.29435801
- Crawford BK, Piault EC, Lai C, Sarzi-Puttini P. Assessing sleep in fibromyalgia: investigation of an alternative scoring method for the Jenkins Sleep Scale based on data from randomized controlled studies. Clin Exp Rheumatol 2010;28:S100–9.
- Sadosky A, Dukes E, Evans C. Reliability of a 1-week recall period for the Medical Outcomes Study Sleep Scale (MOS-SS) in patients with fibromyalgia. Health Qual Life Outc 2009;7:12.
- Cappelleri JC, Bushmakin AG, McDermott AM, Dukes E, Sadosky A, Petrie CD, Martin S. Measurement properties of the Medical Outcomes Study Sleep Scale in patients with fibromyalgia. Sleep Med 2009;10:766–70.19185539
- Hita-Contreras F, Martínez-López E, Latorre-Román PA, Garrido F, Santos MA, Martínez-Amat A. Reliability and validity of the Spanish version of the Pittsburgh Sleep Quality Index (PSQI) in patients with fibromyalgia. Rheumatol Int 2014;34:929–36.24509897
- COSMIN Initiative. Search Filters. URL: www.cosmin.nl/tools/pubmed-search-filters/ (accessed 14 March 2023).
- Hopkins JC, Howes N, Chalmers K, Savovic J, Whale K, Coulman KD, et al.; By-Band Trial Management Group. Outcome reporting in bariatric surgery: an in-depth analysis to inform the development of a core outcome set, the BARIACT Study. Obes Rev 2015;16:88–106.25442513
- Sleep Foundation. Sleep Dictionary. 2022. URL: www.sleepfoundation.org/how-sleep-works/sleep-dictionary (accessed 24 October 2022).
- World Health Organization. International Classification of Functioning, Disability and Health (ICF). 2001. URL: https://icd.who.int/dev11/l-icf/en#/ (accessed 24 October 2022).
- Unal-Ulutatar C, Ozsoy-Unubol T. Psychometric properties of Turkish version of Jenkins Sleep Scale in fibromyalgia syndrome. Adv Rheumatol 2020;60:22.32299495
- Rose RM, Jenkins CD, Hurst MW. Health change in air traffic controllers: a prospective study. I. Background and description. Psychosom Med 1978;40:142–65.652917
- Rose RM, Jenkins CD, Hurst MW. Air Traffic Controller Health Change Study: A Prospective Investigation of Physical, Psychological and Work-related Changes. Washington, DC: Office of Aviation Medicine, Federal Aviation Administration; 1978.
- Jenkins CD, Stanton BA, Savageau JA, Denlinger P, Klein MD. Coronary artery bypass surgery. Physical, psychological, social, and economic outcomes six months later. JAMA 1983;250:782–8.6603521
- Jenkins CD, Stanton BA, Savageau JA, Ockene IS, Denlinger P, Klein MD. Physical, psychologic, social, and economic outcomes after cardiac valve surgery. Arch Intern Med 1983;143:2107–13.6605730
- Patrick DL, Burke LB, Gwaltney CJ, Leidy NK, Martin ML, Molsen E, Ring L. Content validity – establishing and reporting the evidence in newly developed patient-reported outcomes (PRO) instruments for medical product evaluation: ISPOR PRO good research practices task force report: part 1 – eliciting concepts for a new PRO instrument. Value Health 2011;14:967–77.22152165
- Stone KC, Taylor DJ, McCrae CS, Kalsekar A, Lichstein KL. Nonrestorative sleep. Sleep Med Rev 2008;12:275–88.18539057
- Ohayon MM. Prevalence and correlates of nonrestorative sleep complaints. Arch Intern Med 2005;165:35–41.15642872
- REHADAT. b134 Sleep Functions. URL: www.rehadat-icf.de/en/klassifikation/koerperfunktionen/b1/b134/ (accessed 24 October 2022).
- National Institute for Health and Care Research. Improving Inclusion of Under-Served Groups in Clinical Research: Guidance from the NIHR-INCLUDE Project. 2020. URL: www.nihr.ac.uk/documents/improving-inclusion-of-under-served-groups-in-clinical-research-guidance-from-include-project/25435 (accessed 11 November 2022).
Effects of pharmacological and non-pharmacological interventions for the management of sleep problems in people with fibromyalgia: a multi-methods evidence synthesis · References
References
Attribution. Mari Imamura; Clare Robertson; Jemma Hudson; Daniel Whibley; Lorna Aucott; Katie Gillies et al. (2025). Effects of pharmacological and non-pharmacological interventions for the management of sleep problems in people with fibromyalgia: a multi-methods evidence synthesis. National Institute for Health and Care Research. Copyright © 2025 Imamura et al. Licensed under CC BY 4.0. NCBI Bookshelf NBK615175. CC BY 4.0. Original source ↗. Text reproduced from the Bookshelf XML without changing wording; figures, images and supplements are not reproduced.