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Personal Protective Equipment

Diagnostics and Medical Technology · NLM MeSH · updated 2026-11-04 · version 1

Citations verified against PubMedNot yet clinician-reviewed10 referencesApproximately 5 min read

Specialized clothing or equipment worn for protection against health hazards.

Table of Contents

1. Definition2. Research landscape3. Reading the evidence4. Open-access studies5. Key reviews6. References7. About this article

Definition and research guide

This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.

Content available: 4 complete abstracts (932 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.

Definition

Specialized clothing or equipment worn for protection against health hazards. Personal Protective Equipment may include masks; respiratory protective devices; head protective devices; eye protective devices; ear protective devices; protective clothing; and protective footwear.

Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.

Also known as: Equipment, Personal Protective; Personal Protective Equipments; Protective Equipment, Personal; PPE Personal Protective Equipment.

Where it fits in the MeSH classification

Broader topics
Protective Devices
Narrower topics
Ear Protective Devices; Eye Protective Devices; Head Protective Devices; Masks; Mouth Protectors; Protective Clothing; Respiratory Protective Devices

Related concepts

  • Masks
  • Respiratory Protective Devices
  • Head Protective Devices
  • Eye Protective Devices
  • Ear Protective Devices
  • Protective Clothing

Research landscape

PubMed indexes 41,080 records tagged with the MeSH heading “Personal Protective Equipment” (counts retrieved 2026-11-04). 11,673 of them (28.4%) were published from 2020 onward, and the busiest period so far is 2020 onward with 11,673 records.

Reviews account for 3,720 records (9.1%) and meta-analyses for 292. Randomized controlled trials number 2,749 (6.7%) as a share of all records on the topic.

PubMed records by publication periodthrough 1999: 11,349 records; 2000-2009: 8,427 records; 2010-2019: 9,631 records; 2020 onward: 11,673 records11,349through 19998,4272000-20099,6312010-201911,6732020 onward
Records in PubMed indexed with this heading, by publication period. Real counts from NCBI E-utilities; the final period covers only part of the current year. Volume reflects how much has been published, not how strong the evidence is.
Show the data
PeriodRecords
through 199911,349
2000-20098,427
2010-20199,631
2020 onward11,673
Share of records by publication typeReviews: 9.1 percent; Meta-analyses: 0.7 percent; Randomized controlled trials: 6.7 percentReviews9.1% (3,720)Meta-analyses0.7% (292)Randomized controlled trials6.7% (2,749)
Share of all PubMed records on this heading that carry each publication type. Types overlap with other records, so the shares do not sum to 100%.
Publication-type chart data
Publication types among 41,080 PubMed records
TypeRecordsShare
Reviews3,7209.1%
Meta-analyses2920.7%
Randomized controlled trials2,7496.7%

Method: PubMed query "Personal Protective Equipment"[MeSH Terms] with publication-type and date filters, retrieved 2026-11-04.

Reading the evidence in diagnostics and medical technology

A test or device is judged by how well it detects a condition, how often it gives false alarms or misses cases, and whether using it improves outcomes for people. Accuracy depends on who is tested and how common the condition is, so a test that performs well in a specialist hospital can perform differently in the community. Check the reference standard, the population studied, the sensitivity and specificity and whether results were confirmed in a separate group.

Evidence from open-access studies

These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.

Study comparison — selected abstracts, not a systematic review
Study / authorsYearSource label / designEurope PMC citationsLicence / source
The Effect of Music and Eye Masks on Sleep Quality and Delirium in Abdominal Surgery Intensive Care Patients: Randomized Controlled Trial
Topal T, Sürme Y
2025Randomized controlled trial
Design not recorded in structured metadata
6cc by
PMID 40459015 · DOI · PMC12131288
A Wearable AI-Driven Mask with Humidity-Sensing Respiratory Microphone for Non-Vocal Communication
Wang J, Zhang H, Wu X, Gao M, Wen H, Zhang Z, et al.
2025Research article
Design not recorded in structured metadata
3cc by
PMID 40576484 · DOI · PMC12412612
Health Effects of Ergonomics and Personal Protective Equipment on Chemotherapy Professionals
Reis A, Silva V, Joaquim JJ, Valadares L, Matos C, Valeiro C, et al.
2025Review article
Design not recorded in structured metadata
2cc by
PMID 41149483 · DOI · PMC12564291
Direct Integration of Ionic Liquid Gel Sensors onto Microfibrous Face Mask Substrates for Wearable Respiratory Health Monitoring
Qing Z, Choi S, Brown MS, Shanto MAH, Jin Y, Koh A, et al.
2026Research article
Design not recorded in structured metadata
1cc by
PMID 41702671 · DOI · PMC12997150

The Effect of Music and Eye Masks on Sleep Quality and Delirium in Abdominal Surgery Intensive Care Patients: Randomized Controlled Trial [1]

Randomized controlled trial Topal T, Sürme Y · · 2025 · cited 6 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
BackgroundPostoperative delirium is a negative surgical outcome that can affect patients of any age, from children to elderly.
Closing excerpt
Relevance to clinical practiceIntensive care nurses can contribute to improving patients' sleep quality and preventing delirium by applying eye masks and playing music for the patients.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (247 words)

BackgroundPostoperative delirium is a negative surgical outcome that can affect patients of any age, from children to elderly.AimThis study evaluated the impact of eye masks and music on sleep quality and delirium among patients in surgical intensive care units.Study designThis study was designed as a randomized controlled trial. The study sample consisted of 45 patients (21 intervention and 24 control) who were hospitalized in the General Surgery Intensive Care Unit, underwent abdominal surgery and met the inclusion criteria. Patients were assigned to the experimental and control groups by simple randomization method. Patient Identification Form, Richard-Campbell Sleep Questionnaire (RCSQ), Nursing Delirium Screening Scale (Nu-DESC) and Richmond Agitation-Sedation Scale (RASS) were utilized. In the intervention group, patients were left with the eye masks applied after 22:00. Concurrently with the application of the eye masks, calming classical music was played for 1 h. Descriptive statistics, Chi-square test, Student's t-test, one-way analysis of variance (ANOVA), two-way repeated measures ANOVA and linear regression analysis were used. The CONSORT checklist was used in reporting the study.ResultsOn the third day of the study, the mean RCSQ score in the intervention group was statistically higher (72.95 ± 7.47, 49.66 ± 10.80; p ConclusionThe research concluded that listening to calming music for 1 h daily and wearing an eye mask before sleeping increased sleep quality and decreased the incidence of delirium.Relevance to clinical practiceIntensive care nurses can contribute to improving patients' sleep quality and preventing delirium by applying eye masks and playing music for the patients.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 40459015 · DOI · PMC12131288

A Wearable AI-Driven Mask with Humidity-Sensing Respiratory Microphone for Non-Vocal Communication [2]

Research article Wang J, Zhang H, Wu X, Gao M, Wen H, Zhang Z, et al. · · 2025 · cited 3 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
Hoarseness and dysphonia caused by vocal cord conditions or laryngeal surgeries significantly hinder communication and quality of life.
Closing excerpt
With its potential to facilitate naturalistic communication and transform healthcare applications, the HSRM system sets a new benchmark in wearable assistive technologies for voice rehabilitation and human-machine interaction.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (165 words)

Hoarseness and dysphonia caused by vocal cord conditions or laryngeal surgeries significantly hinder communication and quality of life. This study presents a plug-and-play humidity-sensing respiratory microphone (HSRM) with generalized features for individual users. Leveraging gold nanoparticle-based humidity sensors integrated into commercially available wearable face masks, the system enables patients to produce verbal communication without relying on vocal cord activity. By integrating nanoparticle-enhanced humidity sensors with advanced convolutional neural networks, the HSRM system accurately decodes respiratory patterns into intelligible speech, achieving a recognition accuracy of 85.61%. Leveraging nanoparticle-polymer interfaces that effectively convert atmospheric humidity fluctuations into precise electrical signals, the system pioneers a contactless and non-invasive paradigm in assistive speech technology. This innovation addresses limitations of existing devices, such as reliance on residual vocal fold vibrations or skin-contact sensors, offering a practical generalized solution for individuals with aphonia. With its potential to facilitate naturalistic communication and transform healthcare applications, the HSRM system sets a new benchmark in wearable assistive technologies for voice rehabilitation and human-machine interaction.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 40576484 · DOI · PMC12412612

Health Effects of Ergonomics and Personal Protective Equipment on Chemotherapy Professionals [3]

Review article Reis A, Silva V, Joaquim JJ, Valadares L, Matos C, Valeiro C, et al. · · 2025 · cited 2 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
(1) Background: With the increasing incidence of cancer, the need for handling cytotoxic drugs has also grown.
Closing excerpt
Continuous training, rigorous attention to safety procedures, and ergonomic enhancements should be prioritized by healthcare facilities as a key element of occupational safety programs to reduce the short-term and long-term health hazards for personnel handling dangerous drugs.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (303 words)

(1) Background: With the increasing incidence of cancer, the need for handling cytotoxic drugs has also grown. However, manipulating these drugs exposes healthcare professionals to significant risks, including occupational exposure to hazardous chemicals. Therefore, it is important to adopt protective measures, including personal protective equipment (PPE) and correct ergonomic practices, to ensure safe drug preparation and minimize health risks for the operators. However, while chemical exposure and PPE have been extensively addressed in the literature, the combined impact of ergonomic practices and protective measures remains insufficiently emphasized, representing a critical gap this review aims to address. Accordingly, the objective of this literature review was to analyze the ergonomic and individual protection practices during the handling of cytostatic drugs and all the implications that bad ergonomic practices and/or poor individual protection have on the operator's health; (2) Methods: In order to perform this integrative review, a structured literature search was conducted using online databases (Web of Science®, Google Scholar®, and PubMed®) from January 2005 to June 2025. (3) Results: A total of 19 articles were analyzed, with 17 focusing on PPE and 17 on ergonomics. The findings emphasize that PPE, such as gloves, masks, gowns, sleeves and safety glasses, plays a critical role in the safe handling of cytotoxic drugs, particularly when combined with other safety measures. Additionally, maintaining correct ergonomic posture is important in preventing musculoskeletal disorders; (4) Conclusions: This review emphasizes the significance of integrating appropriate PPE use with sound ergonomic procedures. Although PPE is still the secondary line of defense against occupational exposure, ergonomic issues must also be addressed to avoid chronic musculoskeletal problems. Continuous training, rigorous attention to safety procedures, and ergonomic enhancements should be prioritized by healthcare facilities as a key element of occupational safety programs to reduce the short-term and long-term health hazards for personnel handling dangerous drugs.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 41149483 · DOI · PMC12564291

Direct Integration of Ionic Liquid Gel Sensors onto Microfibrous Face Mask Substrates for Wearable Respiratory Health Monitoring [4]

Research article Qing Z, Choi S, Brown MS, Shanto MAH, Jin Y, Koh A, et al. · · 2026 · cited 1 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
Mask-integrated respiratory sensors are promising for noninvasive monitoring of respiratory health outside of clinical settings, for example, to support at-home patient monitoring and telemedicine.
Closing excerpt
Preliminary artificial intelligence (AI) analysis of breathing patterns identifies coughs that are interspersed with regular breathing with 91% accuracy, showing the potential of AI-supported wearable masks for autonomous symptom tracking.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (217 words)

Mask-integrated respiratory sensors are promising for noninvasive monitoring of respiratory health outside of clinical settings, for example, to support at-home patient monitoring and telemedicine. Studies have shown the feasibility of attaching flexible and off-the-shelf sensors to face masks; however, the potential benefits of incorporating sensor materials directly onto the breathable microfibrous mesh of face masks have hardly been explored. In this work, we integrate respiratory sensors on flat polyethylene terephthalate substrates and microfibrous polypropylene face masks using an ionic liquid gel (ILG) to detect changes in local humidity during breathing. Under a DC voltage, the ILG sensors exhibit a superlinear dependence of current on humidity, resulting in enhanced sensitivity at the high humidity levels found in exhaled breath. By varying the composition of the ILG, we find an inverse relationship between the sensing signal strength and sensing kinetics, offering insights into the sensing mechanisms. Freestanding ILG films are found to be resilient under mechanical strain with humidity sensing still possible at 120% strain. Devices that are scalably integrated onto face masks produce sensors that are four times less sensitive to extreme bending at an angle of 150°. Preliminary artificial intelligence (AI) analysis of breathing patterns identifies coughs that are interspersed with regular breathing with 91% accuracy, showing the potential of AI-supported wearable masks for autonomous symptom tracking.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 41702671 · DOI · PMC12997150

Key reviews and meta-analyses

The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.

  • Research article Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis [5]
    Chu DK, Akl EA, Duda S, Solo K, Yaacoub S, Schünemann HJ, et al. · Lancet · 2020 · cited 2,519 times (Europe PMC)
  • Research article An evidence review of face masks against COVID-19 [6]
    Howard J, Huang A, Li Z, Tufekci Z, Zdimal V, van der Westhuizen HM, et al. · Proc Natl Acad Sci U S A · 2021 · cited 752 times (Europe PMC)
  • Research article Contributing factors to personal protective equipment shortages during the COVID-19 pandemic [7]
    Cohen J, Rodgers YVM · Prev Med · 2020 · cited 293 times (Europe PMC)
  • Research article Efficacy of face mask in preventing respiratory virus transmission: A systematic review and meta-analysis [8]
    Liang M, Gao L, Cheng C, Zhou Q, Uy JP, Heiner K, et al. · Travel Med Infect Dis · 2020 · cited 290 times (Europe PMC)
  • Research article Antimicrobial Nanomaterials and Coatings: Current Mechanisms and Future Perspectives to Control the Spread of Viruses Including SARS-CoV-2 [9]
    Imani SM, Ladouceur L, Marshall T, Maclachlan R, Soleymani L, Didar TF · ACS Nano · 2020 · cited 208 times (Europe PMC)
  • Research article Effectiveness of N95 respirators versus surgical masks against influenza: A systematic review and meta-analysis [10]
    Long Y, Hu T, Liu L, Chen R, Guo Q, Yang L, et al. · J Evid Based Med · 2020 · cited 203 times (Europe PMC)

References

  1. Topal T, Sürme Y. The Effect of Music and Eye Masks on Sleep Quality and Delirium in Abdominal Surgery Intensive Care Patients: Randomized Controlled Trial. . 2025. PMID 40459015 · DOI · PMC12131288
  2. Wang J, Zhang H, Wu X, Gao M, Wen H, Zhang Z, et al.. A Wearable AI-Driven Mask with Humidity-Sensing Respiratory Microphone for Non-Vocal Communication. . 2025. PMID 40576484 · DOI · PMC12412612
  3. Reis A, Silva V, Joaquim JJ, Valadares L, Matos C, Valeiro C, et al.. Health Effects of Ergonomics and Personal Protective Equipment on Chemotherapy Professionals. . 2025. PMID 41149483 · DOI · PMC12564291
  4. Qing Z, Choi S, Brown MS, Shanto MAH, Jin Y, Koh A, et al.. Direct Integration of Ionic Liquid Gel Sensors onto Microfibrous Face Mask Substrates for Wearable Respiratory Health Monitoring. . 2026. PMID 41702671 · DOI · PMC12997150
  5. Chu DK, Akl EA, Duda S, Solo K, Yaacoub S, Schünemann HJ, et al.. Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis. Lancet. 2020. PMID 32497510 · DOI · PMC7263814
  6. Howard J, Huang A, Li Z, Tufekci Z, Zdimal V, van der Westhuizen HM, et al.. An evidence review of face masks against COVID-19. Proc Natl Acad Sci U S A. 2021. PMID 33431650 · DOI · PMC7848583
  7. Cohen J, Rodgers YVM. Contributing factors to personal protective equipment shortages during the COVID-19 pandemic. Prev Med. 2020. PMID 33017601 · DOI · PMC7531934
  8. Liang M, Gao L, Cheng C, Zhou Q, Uy JP, Heiner K, et al.. Efficacy of face mask in preventing respiratory virus transmission: A systematic review and meta-analysis. Travel Med Infect Dis. 2020. PMID 32473312 · DOI · PMC7253999
  9. Imani SM, Ladouceur L, Marshall T, Maclachlan R, Soleymani L, Didar TF. Antimicrobial Nanomaterials and Coatings: Current Mechanisms and Future Perspectives to Control the Spread of Viruses Including SARS-CoV-2. ACS Nano. 2020. PMID 33034443 · DOI
  10. Long Y, Hu T, Liu L, Chen R, Guo Q, Yang L, et al.. Effectiveness of N95 respirators versus surgical masks against influenza: A systematic review and meta-analysis. J Evid Based Med. 2020. PMID 32167245 · DOI · PMC7228345

About this article

Sources
NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
Verification
Every reference was resolved against PubMed on 2026-11-04; title, year and DOI matched.
Review state
automated source verified; no human expert review has been recorded yet.
Version
1, last updated 2026-11-04.

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At a glance

41,080
PubMed records on this heading
28%
published since 2020
3,720
review articles
2,749
randomized trials
10
verified references below

Counts come from PubMed on 2026-11-04; they show how much has been written, not how strong the evidence is.

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