Material in this chapter has been reproduced with permission from Elfeky et al.1 and Elfeky et al.2 These are Open Access articles distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: https://creativecommons.org/licenses/by/4.0/. The text below includes minor additions and formatting changes to the original text.
Aim
To conduct an overview of systematic reviews and meta-analyses to answer the research question: For which types of surgery, at which stages of care, in which subgroups of patients and delivered under what conditions are different types of perioperative oxygen therapy clinically effective?
Objectives
- To assess the volume and quality of evidence on perioperative oxygen therapy across different clinical areas through systematically identifying, mapping and summarising available systematic reviews of RCTs.
- To conduct panoramic meta-analyses of the clinical effectiveness of perioperative oxygen therapy across clinical areas by common outcomes.
- To formulate research recommendations by identifying areas of clinical uncertainty where there is either no evidence or insufficient evidence to inform clinical decision-making.