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Uterine Inversion

Kidney, Urology and Women's Health · NLM MeSH · updated 2026-11-04 · version 1

Citations verified against PubMedNot yet clinician-reviewed10 referencesApproximately 5 min read

A complication of obstetric labor in which the corpus of the uterus is forced completely or partially through the uterine cervix.

Table of Contents

1. Definition2. Research landscape3. Reading the evidence4. Open-access studies5. Key reviews6. References7. About this article

Definition and research guide

This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.

Content available: 4 complete abstracts (1,049 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.

Definition

A complication of obstetric labor in which the corpus of the uterus is forced completely or partially through the uterine cervix. This can occur during the late stages of labor and is associated with immediate postpartum hemorrhage.

Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.

Also known as: Inversion, Uterine; Inversion of Uterus; Uterus Inversion.

Where it fits in the MeSH classification

Broader topics
Uterine Diseases; Obstetric Labor Complications

Related concepts

  • Obstetric Labor
  • Uterus
  • Cervix Uteri
  • Postpartum Hemorrhage

Research landscape

PubMed indexes 343 records tagged with the MeSH heading “Uterine Inversion” (counts retrieved 2026-11-04). 48 of them (14.0%) were published from 2020 onward, and the busiest period so far is through 1999 with 108 records.

Reviews account for 31 records (9.0%) and meta-analyses for 0. Randomized controlled trials number 0 (0.0%) as a share of all records on the topic. Randomized trials make up only a small share of this literature, so much of what is known comes from laboratory, observational or descriptive work.

PubMed records by publication periodthrough 1999: 108 records; 2000-2009: 99 records; 2010-2019: 88 records; 2020 onward: 48 records108through 1999992000-2009882010-2019482020 onward
Records in PubMed indexed with this heading, by publication period. Real counts from NCBI E-utilities; the final period covers only part of the current year. Volume reflects how much has been published, not how strong the evidence is.
Show the data
PeriodRecords
through 1999108
2000-200999
2010-201988
2020 onward48
Share of records by publication typeReviews: 9.0 percent; Meta-analyses: 0.0 percent; Randomized controlled trials: 0.0 percentReviews9.0% (31)Meta-analyses0.0% (0)Randomized controlled trials0.0% (0)
Share of all PubMed records on this heading that carry each publication type. Types overlap with other records, so the shares do not sum to 100%.
Publication-type chart data
Publication types among 343 PubMed records
TypeRecordsShare
Reviews319.0%
Meta-analyses00.0%
Randomized controlled trials00.0%

Method: PubMed query "Uterine Inversion"[MeSH Terms] with publication-type and date filters, retrieved 2026-11-04.

Reading the evidence in kidney, urology and women's health

Kidney, urinary and reproductive health research uses lab markers (such as creatinine), imaging, symptom scores and registry data on pregnancy and birth. Findings about pregnancy are especially sensitive to who was studied and when in pregnancy exposure occurred. Nothing on this page is advice about treatment, fertility or pregnancy; speak to a qualified clinician. Check the population, the outcome measured and whether the study accounted for other health differences between groups.

Evidence from open-access studies

These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.

Study comparison — selected abstracts, not a systematic review
Study / authorsYearSource label / designEurope PMC citationsLicence / source
Unusual and delayed presentation of chronic uterine inversion in a young woman as a result of negligence by an untrained birth attendant: a case report
Garg P, Bansal R
2020Research article
Design not recorded in structured metadata
9cc by
PMID 32895057 · DOI · PMC7487847
Acute puerperal uterine inversion with successful manual transvaginal repositioning: A case report
Gao Q, Jiang H, Jia M, Xiong J
2024Research article
Design not recorded in structured metadata
5cc by
PMID 38669392 · DOI · PMC11049735
Total and acute uterine inversion after delivery: a case report
Leal RF, Luz RM, de Almeida JP, Duarte V, Matos I
2014Research article
Design not recorded in structured metadata
5cc by
PMID 25326075 · DOI · PMC4206858
Postpartum acute intrauterine inversion: A case report
An G, Chen W, Liang Z, Zhang L, Zhang Y, Li H, et al.
2025Research article
Design not recorded in structured metadata
0cc by
PMID 40725912 · DOI · PMC12303457

Unusual and delayed presentation of chronic uterine inversion in a young woman as a result of negligence by an untrained birth attendant: a case report [1]

Research article Garg P, Bansal R · · 2020 · cited 9 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
BackgroundUterine inversion is a rare but known complication following parturition and may prove fatal due to neurogenic shock or postpartum hemorrhage if not corrected immediately.
Closing excerpt
ConclusionAwareness of this complication with timely diagnosis and prompt management can significantly minimize maternal morbidity and mortality, especially in a low- and middle-income country such as India, where 70-80% of deliveries still occur in a rural setting with untrained birth attendants.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (407 words)

BackgroundUterine inversion is a rare but known complication following parturition and may prove fatal due to neurogenic shock or postpartum hemorrhage if not corrected immediately. The incidence is variable, occurring in 1 in 2000 to 1 in 50,000 deliveries, as reported in the past. Nowadays, the incidence is declining due to better antenatal care and increasing institutional deliveries. However, in a developing country such as India, due to cultural and financial reasons, most of the deliveries are still being conducted by untrained birth attendants ("dais") who have sparse knowledge of oxytocic drugs. Hence, proper education and training should be imparted to the traditional birth attendants and local village health practitioners about the management of labor, placental delivery, timely diagnosis, and proper management of uterine inversion to avoid this grave complication. We report this case because only a limited number of such cases have been reported so far with delayed presentation of chronic uterine inversion 8 months after delivery as a result of the negligence of an untrained birth attendant.Case presentationWe report a case of a patient with chronic uterine inversion presenting 8 months after childbirth as a result of ignorance at the time of delivery. A 22-year-old P1L1 (Para 1 Live 1) Asian woman of Punjabi ethnicity presented to our institute with a progressively increasing painless vaginal mass along with blood-stained vaginal discharge for the last 6 months and progressive dyspareunia (pain during intercourse) for the last 5 months that had worsened with time. She had experienced a full-term normal vaginal delivery at home 8 months earlier with the assistance of an untrained birth attendant (dai). Her history revealed that she had an unduly prolonged second stage of labor and was given aggressive fundal pressure due to inadequate bearing-down efforts and had collapsed after delivery but was managed conservatively by an untrained birth attendant. A provisional diagnosis of chronic uterine inversion was made on the basis of vaginal findings of a globular mass protruding from the cervix and approaching the vagina with thinning of the cervix around the mass, forming a tight constriction ring, in addition to ultrasound findings. The patient's condition was corrected surgically using Haultain's approach. She had a satisfactory outcome and was discharged symptom-free.ConclusionAwareness of this complication with timely diagnosis and prompt management can significantly minimize maternal morbidity and mortality, especially in a low- and middle-income country such as India, where 70-80% of deliveries still occur in a rural setting with untrained birth attendants.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 32895057 · DOI · PMC7487847

Acute puerperal uterine inversion with successful manual transvaginal repositioning: A case report [2]

Research article Gao Q, Jiang H, Jia M, Xiong J · · 2024 · cited 5 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
RationaleUterine inversion is a rare medical condition that is categorized as puerperal and nonpuerperal.
Closing excerpt
We hope that this case will enable clinicians to better visualize the ultrasound imaging of uterine inversion and the process of manual repositioning.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (189 words)

RationaleUterine inversion is a rare medical condition that is categorized as puerperal and nonpuerperal. Repositioning of uterine involution can be done manually or surgically, the latter of which involves abdominal manipulation and disruption of the integrity of the uterine wall, which can lead to complications for the patient in subsequent pregnancies, such as uterine rupture.Patient concernsWe report a case of acute puerperal uterine inversion that was manually repositioned transvaginally. An ultrasonogram and reset schematic were also presented. A 23-year-old woman (gravida 1 para 0) was admitted to the hospital with a full-term pregnancy.DiagnosesIn the postpartum period, we found placental adhesions and uterine inversion into the uterine cavity, which was confirmed by bedside ultrasound.Interventions and outcomesWe administered analgesic, relieving uterine spasms, and antishock therapy along with manual stripping of the placenta and ultrasound-guided uterine repositioning. After successful repositioning the patient vaginal bleeding decreased rapidly and she was discharged 3 days after delivery.LessonsEarly recognition, antishock therapy and prompt repositioning are key in the management of puerperal uterine inversion. We hope that this case will enable clinicians to better visualize the ultrasound imaging of uterine inversion and the process of manual repositioning.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 38669392 · DOI · PMC11049735

Total and acute uterine inversion after delivery: a case report [3]

Research article Leal RF, Luz RM, de Almeida JP, Duarte V, Matos I · · 2014 · cited 5 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
IntroductionUterine inversion is a rare obstetric emergency that can lead to hypovolemic shock or even maternal death.
Closing excerpt
It is essential to keep in mind this diagnosis, and be updated about the strategies required to solve this complication.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (266 words)

IntroductionUterine inversion is a rare obstetric emergency that can lead to hypovolemic shock or even maternal death. There are many management strategies, but they are poorly described and dispersed in the medical literature. The purpose of this article is to describe a case of complete acute uterine inversion and a review of the literature.Case presentationThe authors describe a case of complete uterine inversion after a normal delivery with fundal placenta and without cord traction, in a 33-year-old Caucasian woman. After the diagnosis was made and after several attempts of manual correction of the inversion, the patient was taken immediately to the operating room and a laparotomy was performed. With opposing pressures in the cervical ring through the abdominal cavity and on the uterus fundus through her vagina, the inversion was resolved. An incision on the cervical ring was unnecessary. Due to incomplete detachment of the placenta the bleeding was mild. She recovered without complications and the histological examination of placenta was unremarkable. In this case, the only risk factor for uterine inversion was the fundal implantation of the placenta.ConclusionsThe low incidence of uterine inversion leads to sparse experience in resolving this obstetrical emergency. The best prognosis occurs in situations where the diagnosis and maneuvers for uterine reversal are made at an early stage. The authors concluded that opposing pressures in the cervical ring through the abdominal cavity and on the uterus fundus through the vagina can resolve the inversion without the need of other surgical techniques. It is essential to keep in mind this diagnosis, and be updated about the strategies required to solve this complication.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 25326075 · DOI · PMC4206858

Postpartum acute intrauterine inversion: A case report [4]

Research article An G, Chen W, Liang Z, Zhang L, Zhang Y, Li H, et al. · · 2025

Abstract reading summary — source excerpts
Opening excerpt
RationaleUterine inversion is a rare and dangerous obstetric emergency, often occurring in the third stage of labor and leading to severe postpartum hemorrhage.
Closing excerpt
It contributes to knowledge on uterine inversion management for researchers and clinicians.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (187 words)

RationaleUterine inversion is a rare and dangerous obstetric emergency, often occurring in the third stage of labor and leading to severe postpartum hemorrhage. It is less common in low-risk pregnant women, yet its prompt management is crucial. This case report fills a gap in the literature by presenting a rare instance in a low-risk young female, offering clinical insights.Patient concernsA low-risk young female had sudden uterine inversion during the third stage of vaginal delivery, with persistent bleeding from the placental site, causing distress and posing an immediate health threat.DiagnosesPhysical examination revealed an abnormal uterine position and inability to contract normally, leading to a diagnosis of severe postpartum hemorrhage due to uterine inversion.InterventionsImmediate medical intervention was carried out to reposition the inverted uterus and control bleeding. After the correction, appropriate measures were taken to ensure stability and prevent complications.OutcomesThe patient's condition was successfully managed, with the inversion corrected and bleeding stopped. Follow-up showed significant improvement and no long-term complications.LessonsThis case emphasizes vigilance for rare complications even in low-risk pregnancies and the need for prompt, coordinated intervention. It contributes to knowledge on uterine inversion management for researchers and clinicians.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 40725912 · DOI · PMC12303457

Key reviews and meta-analyses

The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.

  • Research article Non-puerperal uterine inversion in association with uterine sarcoma: case report in a 26-year-old and review of the literature [5]
    Lupovitch A, England ER, Chen R · Gynecol Oncol · 2005 · cited 40 times (Europe PMC)
  • Research article Uterine inversion: a life-threatening obstetric emergency [6]
    Hostetler DR, Bosworth MF · J Am Board Fam Pract · 2000 · cited 38 times (Europe PMC)
  • Research article Acute uterine inversion: a review of 40 cases [7]
    Baskett TF · J Obstet Gynaecol Can · 2002 · cited 33 times (Europe PMC)
  • Research article Postpartum hemorrhage: abnormally adherent placenta, uterine inversion, and puerperal hematomas [8]
    You WB, Zahn CM · Clin Obstet Gynecol · 2006 · cited 25 times (Europe PMC)
  • Research article Non-haemorrhagic obstetric shock [9]
    Thomson AJ, Greer IA · Baillieres Best Pract Res Clin Obstet Gynaecol · 2000 · cited 24 times (Europe PMC)
  • Research article Uterine Inversion: A Review of a Life-Threatening Obstetrical Emergency [10]
    Wendel MP, Shnaekel KL, Magann EF · Obstet Gynecol Surv · 2018 · cited 22 times (Europe PMC)

References

  1. Garg P, Bansal R. Unusual and delayed presentation of chronic uterine inversion in a young woman as a result of negligence by an untrained birth attendant: a case report. . 2020. PMID 32895057 · DOI · PMC7487847
  2. Gao Q, Jiang H, Jia M, Xiong J. Acute puerperal uterine inversion with successful manual transvaginal repositioning: A case report. . 2024. PMID 38669392 · DOI · PMC11049735
  3. Leal RF, Luz RM, de Almeida JP, Duarte V, Matos I. Total and acute uterine inversion after delivery: a case report. . 2014. PMID 25326075 · DOI · PMC4206858
  4. An G, Chen W, Liang Z, Zhang L, Zhang Y, Li H, et al.. Postpartum acute intrauterine inversion: A case report. . 2025. PMID 40725912 · DOI · PMC12303457
  5. Lupovitch A, England ER, Chen R. Non-puerperal uterine inversion in association with uterine sarcoma: case report in a 26-year-old and review of the literature. Gynecol Oncol. 2005. PMID 15885762 · DOI
  6. Hostetler DR, Bosworth MF. Uterine inversion: a life-threatening obstetric emergency. J Am Board Fam Pract. 2000. PMID 10764194 · DOI
  7. Baskett TF. Acute uterine inversion: a review of 40 cases. J Obstet Gynaecol Can. 2002. PMID 12464994 · DOI
  8. You WB, Zahn CM. Postpartum hemorrhage: abnormally adherent placenta, uterine inversion, and puerperal hematomas. Clin Obstet Gynecol. 2006. PMID 16456355 · DOI
  9. Thomson AJ, Greer IA. Non-haemorrhagic obstetric shock. Baillieres Best Pract Res Clin Obstet Gynaecol. 2000. PMID 10789258 · DOI
  10. Wendel MP, Shnaekel KL, Magann EF. Uterine Inversion: A Review of a Life-Threatening Obstetrical Emergency. Obstet Gynecol Surv. 2018. PMID 30062382 · DOI

About this article

Sources
NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
Verification
Every reference was resolved against PubMed on 2026-11-04; title, year and DOI matched.
Review state
automated source verified; no human expert review has been recorded yet.
Version
1, last updated 2026-11-04.

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At a glance

343
PubMed records on this heading
14%
published since 2020
31
review articles
0
randomized trials
10
verified references below

Counts come from PubMed on 2026-11-04; they show how much has been written, not how strong the evidence is.

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