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Maxilla

Anatomy and Physiology · NLM MeSH · updated 2026-10-31 · version 1

Citations verified against PubMedNot yet clinician-reviewed10 referencesApproximately 5 min read

One of a pair of irregularly shaped bones that form the upper jaw.

Table of Contents

1. Definition2. Research landscape3. Reading the evidence4. Open-access studies5. Key reviews6. References7. About this article

Definition and research guide

This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.

Content available: 4 complete abstracts (949 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.

Definition

One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the orbit, and contains the maxillary sinus.

Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.

Also known as: Maxillas; Maxillae; Maxillary Bone; Bone, Maxillary; Bones, Maxillary; Maxillary Bones.

Where it fits in the MeSH classification

Broader topics
Jaw
See also
Maxillofacial Development

Related concepts

  • Orbit
  • Maxillary Sinus

Research landscape

PubMed indexes 37,364 records tagged with the MeSH heading “Maxilla” (counts retrieved 2026-10-31). 7,086 of them (19.0%) were published from 2020 onward, and the busiest period so far is through 1999 with 11,979 records.

Reviews account for 2,024 records (5.4%) and meta-analyses for 289. Randomized controlled trials number 1,343 (3.6%) as a share of all records on the topic.

PubMed records by publication periodthrough 1999: 11,979 records; 2000-2009: 7,403 records; 2010-2019: 10,896 records; 2020 onward: 7,086 records11,979through 19997,4032000-200910,8962010-20197,0862020 onward
Records in PubMed indexed with this heading, by publication period. Real counts from NCBI E-utilities; the final period covers only part of the current year. Volume reflects how much has been published, not how strong the evidence is.
Show the data
PeriodRecords
through 199911,979
2000-20097,403
2010-201910,896
2020 onward7,086
Share of records by publication typeReviews: 5.4 percent; Meta-analyses: 0.8 percent; Randomized controlled trials: 3.6 percentReviews5.4% (2,024)Meta-analyses0.8% (289)Randomized controlled trials3.6% (1,343)
Share of all PubMed records on this heading that carry each publication type. Types overlap with other records, so the shares do not sum to 100%.
Publication-type chart data
Publication types among 37,364 PubMed records
TypeRecordsShare
Reviews2,0245.4%
Meta-analyses2890.8%
Randomized controlled trials1,3433.6%

Method: PubMed query "Maxilla"[MeSH Terms] with publication-type and date filters, retrieved 2026-10-31.

Reading the evidence in anatomy and physiology

Anatomy describes how body structures are built and physiology describes how they normally work, so most findings here are descriptive or mechanistic rather than evidence about treatment. Much of what is known comes from dissection, imaging, tissue studies and experiments in animals, and measurements in healthy volunteers can differ from those in people with disease or at different ages. Normal ranges vary between individuals and populations. Check whether a result was measured in people or in another species, the age and health of the participants, and the method used.

Evidence from open-access studies

These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.

Study comparison — selected abstracts, not a systematic review
Study / authorsYearSource label / designEurope PMC citationsLicence / source
Evaluation of surgical techniques in survival rate and complications of zygomatic implants for the rehabilitation of the atrophic edentulous maxilla: a systematic review
Kämmerer PW, Fan S, Aparicio C, Bedrossian E, Davó R, Morton D, et al.
2023Systematic review
Design not recorded in structured metadata
35cc by
PMID 37198345 · DOI · PMC10192488
Anatomy of the greater palatine foramen and canal and their clinical significance in relation to the greater palatine artery: a systematic review and meta-analysis
Kim DW, Tempski J, Surma J, Ratusznik J, Raputa W, Świerczek I, et al.
2023Meta-analysis
Design not recorded in structured metadata
21cc by
PMID 36640185 · DOI · PMC9899171
Difference in the alveolar bone remodeling between the adolescents and adults during upper incisor retraction: a retrospective study
Zheng Y, Zhu C, Zhu M, Lei L
2022Research article
Design not recorded in structured metadata
20cc by
PMID 35650260 · DOI · PMC9160063
Augmented Reality of Anatomical Structures of the Maxillomandibular Complex for Learning Dental Radiographic Techniques
Piazza Willig MM, Boessio Vizzotto M, Timm Vieira H, da Silveira Tiecher PF, de Oliveira Gamba T, Assein Arús N, et al.
2026Research article
Design not recorded in structured metadata
1cc by
PMID 41355200 · DOI · PMC13568828

Evaluation of surgical techniques in survival rate and complications of zygomatic implants for the rehabilitation of the atrophic edentulous maxilla: a systematic review [1]

Systematic review Kämmerer PW, Fan S, Aparicio C, Bedrossian E, Davó R, Morton D, et al. · · 2023 · cited 35 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
PurposeTo assess the outcome [zygomatic implant (ZI) survival] and complications of the original surgical technique (OST) and an Anatomy-Guided approach (AGA) in the placement of ZI in patients with severely atrophic maxillae.
Closing excerpt
The utilization of immediate loading protocol is more observed in AGA than in OST.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (263 words)

PurposeTo assess the outcome [zygomatic implant (ZI) survival] and complications of the original surgical technique (OST) and an Anatomy-Guided approach (AGA) in the placement of ZI in patients with severely atrophic maxillae.MethodsTwo independent reviewers conducted an electronic literature search from January 2000 to August 2022. The inclusion criteria were articles reporting at least five patients with severely atrophic edentulous maxilla undergoing placement OST and/or AGA, with a minimum of 6 months of follow-up. Number of patients, defect characteristics, number of ZI, implant details, surgical technique, survival rate, loading protocol, prosthetic rehabilitation, complications, and follow-up period were compared.ResultsTwenty-four studies comprised 2194 ZI in 918 patients with 41 failures. The ZI survival rate was 90.3-100% in OST and 90.4-100% in AGA. Probability of complications with ZI with OST was as follows: sinusitis, 9.53%; soft tissue infection, 7.50%; paresthesia, 10.78%; oroantral fistulas, 4.58%; and direct surgical complication, 6.91%. With AGA, the presenting complications were as follows: sinusitis, 4.39%; soft tissue infection, 4.35%; paresthesia, 0.55%; oroantral fistulas, 1.71%; and direct surgical complication, 1.60%. The prevalence of immediate loading protocol was 22.3% in OST and 89.6% in the AGA. Due to the heterogeneity of studies, statistical comparison was only possible after the descriptive analysis.ConclusionsBased on the current systematic review, placing ZI in severely atrophic edentulous maxillae rehabilitation with the OST and AGA is associated with a high implant survival rate and surgical complications within a minimum of 6 months follow-up. Complications, including sinusitis and soft tissue infection around the implant, are the most common. The utilization of immediate loading protocol is more observed in AGA than in OST.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 37198345 · DOI · PMC10192488

Anatomy of the greater palatine foramen and canal and their clinical significance in relation to the greater palatine artery: a systematic review and meta-analysis [2]

Meta-analysis Kim DW, Tempski J, Surma J, Ratusznik J, Raputa W, Świerczek I, et al. · · 2023 · cited 21 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
PurposeAccurate knowledge of greater palatine foramen (GPF) and greater palatine canal (GPC) anatomy is necessary to avoid injury to the greater palatine artery (GPA) when performing a variety of anesthesiologic, dental or surgical procedures.
Closing excerpt
The results from this evidence-based anatomical study provides a unified set of data to aid clinicians in their practice.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (204 words)

PurposeAccurate knowledge of greater palatine foramen (GPF) and greater palatine canal (GPC) anatomy is necessary to avoid injury to the greater palatine artery (GPA) when performing a variety of anesthesiologic, dental or surgical procedures. The aim of this paper was to perform a systematic review and meta-analysis of literature on the anatomy and localization of bony structures associated with the GPA, namely the GPF and GPC.MethodsA systematic literature search was performed using PubMed, Embase, ScienceDirect, and Web of Science databases. Seventy-five studies were included in the meta-analysis (n = 22,202 subjects).ResultsThe meta-analysis showed that the GPF is positioned 17.21 mm (95% CI = 16.34-18.09 mm) from the posterior nasal spine, 2.56 mm (95% CI = 1.90-3.22 mm) from the posterior border of the hard palate, 46.24 mm (95% CI = 44.30-48.18 mm) from the anterior nasal spine, 15.22 mm (95% CI = 15.00-15.43 mm) from the midline maxillary suture, 37.32 mm (95% CI = 36.19-38.45 mm) from the incisive foramen, and opposite the third maxillary molar (M3) in 64.9% (58.7-70.7%) of the total population.ConclusionAn up-to-date, comprehensive analysis of GPF and GPC clinical anatomy is presented. The results from this evidence-based anatomical study provides a unified set of data to aid clinicians in their practice.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 36640185 · DOI · PMC9899171

Difference in the alveolar bone remodeling between the adolescents and adults during upper incisor retraction: a retrospective study [3]

Research article Zheng Y, Zhu C, Zhu M, Lei L · · 2022 · cited 20 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
The purpose of this study was to compare the difference of alveolar bone remodeling between the adolescents and adults in the maxillary incisor area during retraction.
Closing excerpt
Orthodontists should take the age into consideration to reduce the potential periodontal risks during the treatment planning.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (243 words)

The purpose of this study was to compare the difference of alveolar bone remodeling between the adolescents and adults in the maxillary incisor area during retraction. This retrospective study included 72 female patients who needed moderate anchorage to correct the bimaxillary protrusion. Subjects were further divided into the minor group (n = 36, 11-16 years old) and adult group (n = 36, 18-35 years old). Digital lateral cephalography and cone beam CT scanning were taken in each patient before (T0) and after treatment (T1). Cephalometry was conducted to assess incisor retraction, while alveolar bone thickness (ABT), alveolar bone distance (ABD), and alveolar bone area (ABA) were detected to assess changes in the alveolar bone. No difference in the inclination of upper incisors was observed at both T0 and T1 between two groups. Changes in the alveolar bone showed a similar tendency with bone apposition on the labial side and bone resorption on the palatal side in both groups. Less increase in the labial ABT (T1-T0) and more decrease in the palatal ABT (T1-T0) was found in the adult group, leading to less total ABT in the adult group. Higher reduction in ABD (T1-T0) was found in the adult group. Moreover, more decrease in the ABA (T1-T0) was found in the adult group. Adult patients have less alveolar bone support after treatment when compared with young adolescents. Orthodontists should take the age into consideration to reduce the potential periodontal risks during the treatment planning.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 35650260 · DOI · PMC9160063

Augmented Reality of Anatomical Structures of the Maxillomandibular Complex for Learning Dental Radiographic Techniques [4]

Research article Piazza Willig MM, Boessio Vizzotto M, Timm Vieira H, da Silveira Tiecher PF, de Oliveira Gamba T, Assein Arús N, et al. · · 2026 · cited 1 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
IntroductionAugmented reality (AR) enables interactive learning in real-world environments.
Closing excerpt
Its high usability rating suggests that AR can significantly contribute to improving dental radiography education.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (239 words)

IntroductionAugmented reality (AR) enables interactive learning in real-world environments. In dental radiography education, AR offers a promising tool to enhance students' clinical skills by allowing them to simulate and practice procedures before engaging with actual patients. Repeated practice in an AR environment can reinforce theoretical knowledge and improve practical competence. Understanding dental anatomy and surrounding bone structures is essential for achieving accurate radiographic techniques, and 3D reconstructions from cone-beam computed tomography (CBCT) aid this learning.ObjectiveTo develop and evaluate an AR application designed to support the learning of periapical radiographic techniques.MethodsAn AR application was developed using Digital Imaging and Communication in Medicine (DICOM) images, which were converted into Standard Tessellation Language (STL) format. Meshmixer software was employed to construct a three-dimensional patient model, which was then used to create visual simulations of periapical radiographic projections based on established literature. The resulting images were integrated into the M3DMIX AR platform for visualization. Usability was assessed by 44 undergraduate dental students using a questionnaire based on the System Usability Scale (SUS).ResultsThe AR application achieved a mean usability score of 89.26 on the SUS, indicating a high level of user satisfaction. Students reported that the AR tool positively influenced their learning experience and enhanced their understanding of radiographic techniques.ConclusionThe AR application developed in this study demonstrated strong potential as an effective educational tool for teaching periapical radiographic techniques. Its high usability rating suggests that AR can significantly contribute to improving dental radiography education.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 41355200 · DOI · PMC13568828

Key reviews and meta-analyses

The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.

  • Research article A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation [5]
    Pjetursson BE, Tan WC, Zwahlen M, Lang NP · J Clin Periodontol · 2008 · cited 519 times (Europe PMC)
  • Research article Reconstruction of the maxilla and midface: introducing a new classification [6]
    Brown JS, Shaw RJ · Lancet Oncol · 2010 · cited 347 times (Europe PMC)
  • Research article A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation. Part II: transalveolar technique [7]
    Tan WC, Lang NP, Zwahlen M, Pjetursson BE · J Clin Periodontol · 2008 · cited 236 times (Europe PMC)
  • Research article Systematic review of survival rates for implants placed in the grafted maxillary sinus [8]
    Del Fabbro M, Testori T, Francetti L, Weinstein R · Int J Periodontics Restorative Dent · 2004 · cited 225 times (Europe PMC)
  • Research article Intraoral Scanner Technologies: A Review to Make a Successful Impression [9]
    Richert R, Goujat A, Venet L, Viguie G, Viennot S, Robinson P, et al. · J Healthc Eng · 2017 · cited 223 times (Europe PMC)
  • Research article A meta-analysis of cleft maxillary osteotomy and distraction osteogenesis [10]
    Cheung LK, Chua HD · Int J Oral Maxillofac Surg · 2006 · cited 117 times (Europe PMC)

References

  1. Kämmerer PW, Fan S, Aparicio C, Bedrossian E, Davó R, Morton D, et al.. Evaluation of surgical techniques in survival rate and complications of zygomatic implants for the rehabilitation of the atrophic edentulous maxilla: a systematic review. . 2023. PMID 37198345 · DOI · PMC10192488
  2. Kim DW, Tempski J, Surma J, Ratusznik J, Raputa W, Świerczek I, et al.. Anatomy of the greater palatine foramen and canal and their clinical significance in relation to the greater palatine artery: a systematic review and meta-analysis. . 2023. PMID 36640185 · DOI · PMC9899171
  3. Zheng Y, Zhu C, Zhu M, Lei L. Difference in the alveolar bone remodeling between the adolescents and adults during upper incisor retraction: a retrospective study. . 2022. PMID 35650260 · DOI · PMC9160063
  4. Piazza Willig MM, Boessio Vizzotto M, Timm Vieira H, da Silveira Tiecher PF, de Oliveira Gamba T, Assein Arús N, et al.. Augmented Reality of Anatomical Structures of the Maxillomandibular Complex for Learning Dental Radiographic Techniques. . 2026. PMID 41355200 · DOI · PMC13568828
  5. Pjetursson BE, Tan WC, Zwahlen M, Lang NP. A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation. J Clin Periodontol. 2008. PMID 18724852 · DOI
  6. Brown JS, Shaw RJ. Reconstruction of the maxilla and midface: introducing a new classification. Lancet Oncol. 2010. PMID 20932492 · DOI
  7. Tan WC, Lang NP, Zwahlen M, Pjetursson BE. A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation. Part II: transalveolar technique. J Clin Periodontol. 2008. PMID 18724853 · DOI
  8. Del Fabbro M, Testori T, Francetti L, Weinstein R. Systematic review of survival rates for implants placed in the grafted maxillary sinus. Int J Periodontics Restorative Dent. 2004. PMID 15626319
  9. Richert R, Goujat A, Venet L, Viguie G, Viennot S, Robinson P, et al.. Intraoral Scanner Technologies: A Review to Make a Successful Impression. J Healthc Eng. 2017. PMID 29065652 · DOI · PMC5605789
  10. Cheung LK, Chua HD. A meta-analysis of cleft maxillary osteotomy and distraction osteogenesis. Int J Oral Maxillofac Surg. 2006. PMID 16154316 · DOI

About this article

Sources
NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
Verification
Every reference was resolved against PubMed on 2026-10-31; title, year and DOI matched.
Review state
automated source verified; no human expert review has been recorded yet.
Version
1, last updated 2026-10-31.

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At a glance

37,364
PubMed records on this heading
19%
published since 2020
2,024
review articles
1,343
randomized trials
10
verified references below

Counts come from PubMed on 2026-10-31; they show how much has been written, not how strong the evidence is.

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