Definition and research guide
This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.
Content available: 4 complete abstracts (949 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.
Definition
One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the orbit, and contains the maxillary sinus.
Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.
Also known as: Maxillas; Maxillae; Maxillary Bone; Bone, Maxillary; Bones, Maxillary; Maxillary Bones.
Where it fits in the MeSH classification
- Broader topics
- Jaw
- See also
- Maxillofacial Development
Related concepts
- Orbit
- Maxillary Sinus
Research landscape
PubMed indexes 37,364 records tagged with the MeSH heading “Maxilla” (counts retrieved 2026-10-31). 7,086 of them (19.0%) were published from 2020 onward, and the busiest period so far is through 1999 with 11,979 records.
Reviews account for 2,024 records (5.4%) and meta-analyses for 289. Randomized controlled trials number 1,343 (3.6%) as a share of all records on the topic.
Show the data
| Period | Records |
|---|---|
| through 1999 | 11,979 |
| 2000-2009 | 7,403 |
| 2010-2019 | 10,896 |
| 2020 onward | 7,086 |
Publication-type chart data
| Type | Records | Share |
|---|---|---|
| Reviews | 2,024 | 5.4% |
| Meta-analyses | 289 | 0.8% |
| Randomized controlled trials | 1,343 | 3.6% |
Method: PubMed query "Maxilla"[MeSH Terms] with publication-type and date filters, retrieved 2026-10-31.
Reading the evidence in anatomy and physiology
Anatomy describes how body structures are built and physiology describes how they normally work, so most findings here are descriptive or mechanistic rather than evidence about treatment. Much of what is known comes from dissection, imaging, tissue studies and experiments in animals, and measurements in healthy volunteers can differ from those in people with disease or at different ages. Normal ranges vary between individuals and populations. Check whether a result was measured in people or in another species, the age and health of the participants, and the method used.
Evidence from open-access studies
These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.
Evaluation of surgical techniques in survival rate and complications of zygomatic implants for the rehabilitation of the atrophic edentulous maxilla: a systematic review [1]
Abstract reading summary — source excerpts
- Opening excerpt
- PurposeTo assess the outcome [zygomatic implant (ZI) survival] and complications of the original surgical technique (OST) and an Anatomy-Guided approach (AGA) in the placement of ZI in patients with severely atrophic maxillae.
- Closing excerpt
- The utilization of immediate loading protocol is more observed in AGA than in OST.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (263 words)
PurposeTo assess the outcome [zygomatic implant (ZI) survival] and complications of the original surgical technique (OST) and an Anatomy-Guided approach (AGA) in the placement of ZI in patients with severely atrophic maxillae.MethodsTwo independent reviewers conducted an electronic literature search from January 2000 to August 2022. The inclusion criteria were articles reporting at least five patients with severely atrophic edentulous maxilla undergoing placement OST and/or AGA, with a minimum of 6 months of follow-up. Number of patients, defect characteristics, number of ZI, implant details, surgical technique, survival rate, loading protocol, prosthetic rehabilitation, complications, and follow-up period were compared.ResultsTwenty-four studies comprised 2194 ZI in 918 patients with 41 failures. The ZI survival rate was 90.3-100% in OST and 90.4-100% in AGA. Probability of complications with ZI with OST was as follows: sinusitis, 9.53%; soft tissue infection, 7.50%; paresthesia, 10.78%; oroantral fistulas, 4.58%; and direct surgical complication, 6.91%. With AGA, the presenting complications were as follows: sinusitis, 4.39%; soft tissue infection, 4.35%; paresthesia, 0.55%; oroantral fistulas, 1.71%; and direct surgical complication, 1.60%. The prevalence of immediate loading protocol was 22.3% in OST and 89.6% in the AGA. Due to the heterogeneity of studies, statistical comparison was only possible after the descriptive analysis.ConclusionsBased on the current systematic review, placing ZI in severely atrophic edentulous maxillae rehabilitation with the OST and AGA is associated with a high implant survival rate and surgical complications within a minimum of 6 months follow-up. Complications, including sinusitis and soft tissue infection around the implant, are the most common. The utilization of immediate loading protocol is more observed in AGA than in OST.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 37198345 · DOI · PMC10192488
Anatomy of the greater palatine foramen and canal and their clinical significance in relation to the greater palatine artery: a systematic review and meta-analysis [2]
Abstract reading summary — source excerpts
- Opening excerpt
- PurposeAccurate knowledge of greater palatine foramen (GPF) and greater palatine canal (GPC) anatomy is necessary to avoid injury to the greater palatine artery (GPA) when performing a variety of anesthesiologic, dental or surgical procedures.
- Closing excerpt
- The results from this evidence-based anatomical study provides a unified set of data to aid clinicians in their practice.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (204 words)
PurposeAccurate knowledge of greater palatine foramen (GPF) and greater palatine canal (GPC) anatomy is necessary to avoid injury to the greater palatine artery (GPA) when performing a variety of anesthesiologic, dental or surgical procedures. The aim of this paper was to perform a systematic review and meta-analysis of literature on the anatomy and localization of bony structures associated with the GPA, namely the GPF and GPC.MethodsA systematic literature search was performed using PubMed, Embase, ScienceDirect, and Web of Science databases. Seventy-five studies were included in the meta-analysis (n = 22,202 subjects).ResultsThe meta-analysis showed that the GPF is positioned 17.21 mm (95% CI = 16.34-18.09 mm) from the posterior nasal spine, 2.56 mm (95% CI = 1.90-3.22 mm) from the posterior border of the hard palate, 46.24 mm (95% CI = 44.30-48.18 mm) from the anterior nasal spine, 15.22 mm (95% CI = 15.00-15.43 mm) from the midline maxillary suture, 37.32 mm (95% CI = 36.19-38.45 mm) from the incisive foramen, and opposite the third maxillary molar (M3) in 64.9% (58.7-70.7%) of the total population.ConclusionAn up-to-date, comprehensive analysis of GPF and GPC clinical anatomy is presented. The results from this evidence-based anatomical study provides a unified set of data to aid clinicians in their practice.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 36640185 · DOI · PMC9899171
Difference in the alveolar bone remodeling between the adolescents and adults during upper incisor retraction: a retrospective study [3]
Abstract reading summary — source excerpts
- Opening excerpt
- The purpose of this study was to compare the difference of alveolar bone remodeling between the adolescents and adults in the maxillary incisor area during retraction.
- Closing excerpt
- Orthodontists should take the age into consideration to reduce the potential periodontal risks during the treatment planning.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (243 words)
The purpose of this study was to compare the difference of alveolar bone remodeling between the adolescents and adults in the maxillary incisor area during retraction. This retrospective study included 72 female patients who needed moderate anchorage to correct the bimaxillary protrusion. Subjects were further divided into the minor group (n = 36, 11-16 years old) and adult group (n = 36, 18-35 years old). Digital lateral cephalography and cone beam CT scanning were taken in each patient before (T0) and after treatment (T1). Cephalometry was conducted to assess incisor retraction, while alveolar bone thickness (ABT), alveolar bone distance (ABD), and alveolar bone area (ABA) were detected to assess changes in the alveolar bone. No difference in the inclination of upper incisors was observed at both T0 and T1 between two groups. Changes in the alveolar bone showed a similar tendency with bone apposition on the labial side and bone resorption on the palatal side in both groups. Less increase in the labial ABT (T1-T0) and more decrease in the palatal ABT (T1-T0) was found in the adult group, leading to less total ABT in the adult group. Higher reduction in ABD (T1-T0) was found in the adult group. Moreover, more decrease in the ABA (T1-T0) was found in the adult group. Adult patients have less alveolar bone support after treatment when compared with young adolescents. Orthodontists should take the age into consideration to reduce the potential periodontal risks during the treatment planning.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 35650260 · DOI · PMC9160063
Augmented Reality of Anatomical Structures of the Maxillomandibular Complex for Learning Dental Radiographic Techniques [4]
Abstract reading summary — source excerpts
- Opening excerpt
- IntroductionAugmented reality (AR) enables interactive learning in real-world environments.
- Closing excerpt
- Its high usability rating suggests that AR can significantly contribute to improving dental radiography education.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (239 words)
IntroductionAugmented reality (AR) enables interactive learning in real-world environments. In dental radiography education, AR offers a promising tool to enhance students' clinical skills by allowing them to simulate and practice procedures before engaging with actual patients. Repeated practice in an AR environment can reinforce theoretical knowledge and improve practical competence. Understanding dental anatomy and surrounding bone structures is essential for achieving accurate radiographic techniques, and 3D reconstructions from cone-beam computed tomography (CBCT) aid this learning.ObjectiveTo develop and evaluate an AR application designed to support the learning of periapical radiographic techniques.MethodsAn AR application was developed using Digital Imaging and Communication in Medicine (DICOM) images, which were converted into Standard Tessellation Language (STL) format. Meshmixer software was employed to construct a three-dimensional patient model, which was then used to create visual simulations of periapical radiographic projections based on established literature. The resulting images were integrated into the M3DMIX AR platform for visualization. Usability was assessed by 44 undergraduate dental students using a questionnaire based on the System Usability Scale (SUS).ResultsThe AR application achieved a mean usability score of 89.26 on the SUS, indicating a high level of user satisfaction. Students reported that the AR tool positively influenced their learning experience and enhanced their understanding of radiographic techniques.ConclusionThe AR application developed in this study demonstrated strong potential as an effective educational tool for teaching periapical radiographic techniques. Its high usability rating suggests that AR can significantly contribute to improving dental radiography education.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 41355200 · DOI · PMC13568828
Key reviews and meta-analyses
The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.
- Research article A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation [5]
- Research article Reconstruction of the maxilla and midface: introducing a new classification [6]
- Research article A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation. Part II: transalveolar technique [7]
- Research article Systematic review of survival rates for implants placed in the grafted maxillary sinus [8]
- Research article Intraoral Scanner Technologies: A Review to Make a Successful Impression [9]
- Research article A meta-analysis of cleft maxillary osteotomy and distraction osteogenesis [10]
References
- Kämmerer PW, Fan S, Aparicio C, Bedrossian E, Davó R, Morton D, et al.. Evaluation of surgical techniques in survival rate and complications of zygomatic implants for the rehabilitation of the atrophic edentulous maxilla: a systematic review. . 2023. PMID 37198345 · DOI · PMC10192488
- Kim DW, Tempski J, Surma J, Ratusznik J, Raputa W, Świerczek I, et al.. Anatomy of the greater palatine foramen and canal and their clinical significance in relation to the greater palatine artery: a systematic review and meta-analysis. . 2023. PMID 36640185 · DOI · PMC9899171
- Zheng Y, Zhu C, Zhu M, Lei L. Difference in the alveolar bone remodeling between the adolescents and adults during upper incisor retraction: a retrospective study. . 2022. PMID 35650260 · DOI · PMC9160063
- Piazza Willig MM, Boessio Vizzotto M, Timm Vieira H, da Silveira Tiecher PF, de Oliveira Gamba T, Assein Arús N, et al.. Augmented Reality of Anatomical Structures of the Maxillomandibular Complex for Learning Dental Radiographic Techniques. . 2026. PMID 41355200 · DOI · PMC13568828
- Pjetursson BE, Tan WC, Zwahlen M, Lang NP. A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation. J Clin Periodontol. 2008. PMID 18724852 · DOI
- Brown JS, Shaw RJ. Reconstruction of the maxilla and midface: introducing a new classification. Lancet Oncol. 2010. PMID 20932492 · DOI
- Tan WC, Lang NP, Zwahlen M, Pjetursson BE. A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation. Part II: transalveolar technique. J Clin Periodontol. 2008. PMID 18724853 · DOI
- Del Fabbro M, Testori T, Francetti L, Weinstein R. Systematic review of survival rates for implants placed in the grafted maxillary sinus. Int J Periodontics Restorative Dent. 2004. PMID 15626319
- Richert R, Goujat A, Venet L, Viguie G, Viennot S, Robinson P, et al.. Intraoral Scanner Technologies: A Review to Make a Successful Impression. J Healthc Eng. 2017. PMID 29065652 · DOI · PMC5605789
- Cheung LK, Chua HD. A meta-analysis of cleft maxillary osteotomy and distraction osteogenesis. Int J Oral Maxillofac Surg. 2006. PMID 16154316 · DOI
About this article
- Sources
- NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
- Verification
- Every reference was resolved against PubMed on 2026-10-31; title, year and DOI matched.
- Review state
- automated source verified; no human expert review has been recorded yet.
- Version
- 1, last updated 2026-10-31.
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Evidence strength
EvidenceHelix's computed view of the study designs behind this topic: how common meta-analyses, randomized trials and reviews are, how recent the literature is, and a plain-language reading. It describes the design mix of the literature. It is not a quality appraisal of any study, and it is not medical advice.