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Chin

Anatomy and Physiology · NLM MeSH · updated 2026-10-31 · version 1

Citations verified against PubMedNot yet clinician-reviewed10 referencesApproximately 5 min read

The anatomical frontal portion of the mandible, also known as the mentum, that contains the line of fusion of the two separate halves of the mandible (symphysis menti).

Table of Contents

1. Definition2. Research landscape3. Reading the evidence4. Open-access studies5. Key reviews6. References7. About this article

Definition and research guide

This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.

Content available: 4 complete abstracts (967 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.

Definition

The anatomical frontal portion of the mandible, also known as the mentum, that contains the line of fusion of the two separate halves of the mandible (symphysis menti). This line of fusion divides inferiorly to enclose a triangular area called the mental protuberance. On each side, inferior to the second premolar tooth, is the mental foramen for the passage of blood vessels and a nerve.

Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.

Also known as: Mental Region; Mentum.

Where it fits in the MeSH classification

Broader topics
Face; Mandible

Research landscape

PubMed indexes 4,318 records tagged with the MeSH heading “Chin” (counts retrieved 2026-10-31). 473 of them (11.0%) were published from 2020 onward, and the busiest period so far is through 1999 with 1,657 records.

Reviews account for 233 records (5.4%) and meta-analyses for 10. Randomized controlled trials number 106 (2.5%) as a share of all records on the topic.

PubMed records by publication periodthrough 1999: 1,657 records; 2000-2009: 964 records; 2010-2019: 1,224 records; 2020 onward: 473 records1,657through 19999642000-20091,2242010-20194732020 onward
Records in PubMed indexed with this heading, by publication period. Real counts from NCBI E-utilities; the final period covers only part of the current year. Volume reflects how much has been published, not how strong the evidence is.
Show the data
PeriodRecords
through 19991,657
2000-2009964
2010-20191,224
2020 onward473
Share of records by publication typeReviews: 5.4 percent; Meta-analyses: 0.2 percent; Randomized controlled trials: 2.5 percentReviews5.4% (233)Meta-analyses0.2% (10)Randomized controlled trials2.5% (106)
Share of all PubMed records on this heading that carry each publication type. Types overlap with other records, so the shares do not sum to 100%.
Publication-type chart data
Publication types among 4,318 PubMed records
TypeRecordsShare
Reviews2335.4%
Meta-analyses100.2%
Randomized controlled trials1062.5%

Method: PubMed query "Chin"[MeSH Terms] with publication-type and date filters, retrieved 2026-10-31.

Reading the evidence in anatomy and physiology

Anatomy describes how body structures are built and physiology describes how they normally work, so most findings here are descriptive or mechanistic rather than evidence about treatment. Much of what is known comes from dissection, imaging, tissue studies and experiments in animals, and measurements in healthy volunteers can differ from those in people with disease or at different ages. Normal ranges vary between individuals and populations. Check whether a result was measured in people or in another species, the age and health of the participants, and the method used.

Evidence from open-access studies

These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.

Study comparison — selected abstracts, not a systematic review
Study / authorsYearSource label / designEurope PMC citationsLicence / source
Vertical ridge augmentation of the atrophic posterior mandible with sandwich technique: bone block from the chin area versus corticocancellous bone block allograft--clinical and histological prospective randomized controlled study
Laino L, Iezzi G, Piattelli A, Lo Muzio L, Cicciù M
2014Randomized controlled trial
Design not recorded in structured metadata
66cc by
PMID 24877155 · DOI · PMC4020564
Influence of the chin-down and chin-tuck maneuver on the swallowing kinematics of healthy adults
Leigh JH, Oh BM, Seo HG, Lee GJ, Min Y, Kim K, et al.
2015Research article
Design not recorded in structured metadata
36cc by
PMID 25358491 · DOI · PMC4342518
Preliminary clinical experience of robot-assisted surgery in treatment with genioplasty
Lin L, Xu C, Shi Y, Zhou C, Zhu M, Chai G, et al.
2021Research article
Design not recorded in structured metadata
26cc by
PMID 33739026 · DOI · PMC7973719
3-dimensional analysis of hard- and soft-tissue symmetry in a Chinese population
Zhao J, Xu Y, Wang J, Lu Z, Qi K
2023Research article
Design not recorded in structured metadata
16cc by
PMID 37386472 · DOI · PMC10308641

Vertical ridge augmentation of the atrophic posterior mandible with sandwich technique: bone block from the chin area versus corticocancellous bone block allograft--clinical and histological prospective randomized controlled study [1]

Randomized controlled trial Laino L, Iezzi G, Piattelli A, Lo Muzio L, Cicciù M · · 2014 · cited 66 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
UnlabelledThe aim of the present study is to compare the histological aspects of bone formation in atrophic posterior mandibles augmented by autologous bone block from chin area with corticocancellous bone block allograft used as inlays with the sandwich technique.
Closing excerpt
ConclusionsIn conclusion, both procedures supported good results, although the use of bone blocks allograft was less invasive and preferable than harvesting bone from the mental symphysis.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (197 words)

UnlabelledThe aim of the present study is to compare the histological aspects of bone formation in atrophic posterior mandibles augmented by autologous bone block from chin area with corticocancellous bone block allograft used as inlays with the sandwich technique.Materials and methodsSixteen patients with bilateral partial edentulism in the posterior mandible were selected. The residual bone height, preliminarily measured by computed tomography scans, ranged between 5 and 7 mm from the inferior alveolar nerve. All patients required regeneration procedure with autologous bone block from chin area (control group) versus bone block allograft Puros (Zimmer Dental, 1900 Aston Avenue, Carlsbad, CA, USA) (test group). Histological and histomorphometric samples were collected at the time of implant positioning in order to analyze the percentage of newly formed bone, the residual graft material, and marrow spaces/soft tissue.ResultsNo statistically significant differences between the two groups were found regarding the percentage of newly formed bone. The percentage of residual grafted material was significantly higher in the test group, whilst the percentage of marrow spaces was higher in control group.ConclusionsIn conclusion, both procedures supported good results, although the use of bone blocks allograft was less invasive and preferable than harvesting bone from the mental symphysis.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 24877155 · DOI · PMC4020564

Influence of the chin-down and chin-tuck maneuver on the swallowing kinematics of healthy adults [2]

Research article Leigh JH, Oh BM, Seo HG, Lee GJ, Min Y, Kim K, et al. · · 2015 · cited 36 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
The purpose of the study was to investigate the influence of the chin-tuck maneuver on the movements of swallowing-related structures in healthy subjects and formulate standard instructions for the maneuver.
Closing excerpt
Comparing DOWN and TUCK, only TUCK induced significant changes in the airway entrance, hyoid movement, and epiglottic base retraction.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (273 words)

The purpose of the study was to investigate the influence of the chin-tuck maneuver on the movements of swallowing-related structures in healthy subjects and formulate standard instructions for the maneuver. A total of 40 healthy volunteers (20 men and 20 women) swallowed 10 mL of diluted barium solution in a "normal and comfortable" position (NEUT), a comfortable chin-down position (DOWN), and a strict chin-tuck position (TUCK). Resting state anatomy and kinematic changes were analyzed and compared between postures. Although angles of anterior cervical flexion were comparable between DOWN (46.65 ± 9.69 degrees) and TUCK (43.27 ± 12.20), the chin-to-spine distance was significantly shorter in TUCK than in other positions. Only TUCK showed a significantly shorter anteroposterior diameter of the laryngeal inlet (TUCK vs. NEUT, 14.0 ± 4.3 vs. 16.3 ± 5.0 mm) and the oropharynx (18.8 ± 3.1 vs. 20.5 ± 2.8 mm) at rest. The maximal horizontal displacement of the hyoid bone was significantly less in TUCK (9.6 ± 3.0 mm) than in NEUT (12.6 ± 2.6 mm; p < 0.01) or DOWN (12.1 ± 3.0 mm; p < 0.01). TUCK facilitated movement of the epiglottic base upward (TUCK vs. NEUT, 15.8 ± 4.7 vs. 13.3 ± 4.5 mm; p < 0.01). In contrast, DOWN increased the horizontal excursion of the epiglottic base and reduced movement of the vocal cords. These results quantitatively elucidated the biomechanical influences of the chin-tuck maneuver including reduced horizontal movement of the hyoid bone, facilitation of vertical movement of the epiglottic base, and narrowing of the airway entrance. Comparing DOWN and TUCK, only TUCK induced significant changes in the airway entrance, hyoid movement, and epiglottic base retraction.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 25358491 · DOI · PMC4342518

Preliminary clinical experience of robot-assisted surgery in treatment with genioplasty [3]

Research article Lin L, Xu C, Shi Y, Zhou C, Zhu M, Chai G, et al. · · 2021 · cited 26 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
Genioplasty is the main way to treat diseases such as chin asymmetry, dysplasia and overdevelopment, which involve the three-dimensional direction abnormalities of the chin.
Closing excerpt
Based on the early results of 6 patients, the robot-assisted approach appears to be a safe and effective strategy for genioplasty.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (193 words)

Genioplasty is the main way to treat diseases such as chin asymmetry, dysplasia and overdevelopment, which involve the three-dimensional direction abnormalities of the chin. Since this kind of surgery mainly uses intraoral incisions, the narrow surgical field of intraoral incisions and the surrounding important neurovascular tissues make it easy for complications, to occur during the osteotomy process, which results in greater surgical risks. The first craniofacial-plastic surgical robot (CPSR-I) system is developed to complete the precise positioning and improve the surgeon's force perception ability. The Kalman filtering method is adopted to reduce the interference of sensor signal noise. An adaptive fuzzy control system, which has strong robustness and adaptability to the environment, is designed to improve the stability of robot-assisted surgical operations. To solve the problem of the depth perception, we propose an automatic bone drilling control strategy that combines position and force conditions to ensure that the robot can automatically stop when the bone is penetrated. On the basis of model surgery and animal experiments, preliminary experiments were carried out clinically. Based on the early results of 6 patients, the robot-assisted approach appears to be a safe and effective strategy for genioplasty.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 33739026 · DOI · PMC7973719

3-dimensional analysis of hard- and soft-tissue symmetry in a Chinese population [4]

Research article Zhao J, Xu Y, Wang J, Lu Z, Qi K · · 2023 · cited 16 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
BackgroundFacial symmetry severely affects appearance and function.
Closing excerpt
Soft-tissue asymmetry might be reduced by improving the dentition in individuals with RS group, while among those with MA or SA, whose menton deviation was larger than 2 mm, orthognathic treatment should be considered.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (304 words)

BackgroundFacial symmetry severely affects appearance and function. Large numbers of patients seek orthodontic treatment to improve facial symmetry. However, the correlation between hard- and soft-tissue symmetry is still unclear. Our aim was to investigate the hard- and soft-tissue symmetry in subjects with different levels of menton deviation and sagittal skeletal classes with 3D digital analysis and to investigate the relationship between the entire and individual hard- and soft-tissues.MethodsA total of 270 adults (135 males and 135 females) consisting of 45 subjects of each sex in each sagittal skeletal classification group. All subjects were further classified into relative symmetry (RS), moderate asymmetry (MA) and severe asymmetry (SA) groups based on the degree of menton deviation from the mid-sagittal plane (MSP). The 3D images were segmented into anatomical structures and mirrored across the MSP after establishing a coordinate system. Original and mirrored images were registered by a best-fit algorithm, and the corresponding root mean square (RMS) values and colormap were obtained. The Mann‒Whitney U test and Spearman correlation were conducted for statistical analysis.ResultsThe RMS increased with greater deviations with regard to the deviation of the menton in most of anatomical structures. Asymmetry was represented in the same way regardless of sagittal skeletal pattern. The soft-tissue asymmetry had a significant correlation with dentition in the RS group (0.409), while in the SA group, it was related to the ramus (0.526) and corpus (0.417) in males and was related to the ramus in the MA (0.332) and SA (0.359) groups in females.ConclusionsThe mirroring method combining CBCT and 3dMD provides a new approach for symmetry analysis. Asymmetry might not be influenced by sagittal skeletal patterns. Soft-tissue asymmetry might be reduced by improving the dentition in individuals with RS group, while among those with MA or SA, whose menton deviation was larger than 2 mm, orthognathic treatment should be considered.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 37386472 · DOI · PMC10308641

Key reviews and meta-analyses

The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.

  • Research article The mental foramen and nerve: clinical and anatomical factors related to dental implant placement: a literature review [5]
    Greenstein G, Tarnow D · J Periodontol · 2006 · cited 220 times (Europe PMC)
  • Research article The human chin revisited: what is it and who has it? [6]
    Schwartz JH, Tattersall I · J Hum Evol · 2000 · cited 76 times (Europe PMC)
  • Research article Soft tissue response to mandibular advancement and genioplasty [7]
    Ewing M, Ross RB · Am J Orthod Dentofacial Orthop · 1992 · cited 58 times (Europe PMC)
  • Research article A retrospective study of advancement genioplasty [8]
    Park HS, Ellis E, Fonseca RJ, Reynolds ST, Mayo KH · Oral Surg Oral Med Oral Pathol · 1989 · cited 50 times (Europe PMC)
  • Research article Role of Nonsurgical Chin Augmentation in Full Face Rejuvenation: A Review and Our Experience [9]
    Vanaman Wilson MJ, Jones IT, Butterwick K, Fabi SG · Dermatol Surg · 2018 · cited 43 times (Europe PMC)
  • Research article Feminization of the Chin: Genioplasty Using Osteotomies [10]
    Deschamps-Braly J · Facial Plast Surg Clin North Am · 2019 · cited 41 times (Europe PMC)

References

  1. Laino L, Iezzi G, Piattelli A, Lo Muzio L, Cicciù M. Vertical ridge augmentation of the atrophic posterior mandible with sandwich technique: bone block from the chin area versus corticocancellous bone block allograft--clinical and histological prospective randomized controlled study. . 2014. PMID 24877155 · DOI · PMC4020564
  2. Leigh JH, Oh BM, Seo HG, Lee GJ, Min Y, Kim K, et al.. Influence of the chin-down and chin-tuck maneuver on the swallowing kinematics of healthy adults. . 2015. PMID 25358491 · DOI · PMC4342518
  3. Lin L, Xu C, Shi Y, Zhou C, Zhu M, Chai G, et al.. Preliminary clinical experience of robot-assisted surgery in treatment with genioplasty. . 2021. PMID 33739026 · DOI · PMC7973719
  4. Zhao J, Xu Y, Wang J, Lu Z, Qi K. 3-dimensional analysis of hard- and soft-tissue symmetry in a Chinese population. . 2023. PMID 37386472 · DOI · PMC10308641
  5. Greenstein G, Tarnow D. The mental foramen and nerve: clinical and anatomical factors related to dental implant placement: a literature review. J Periodontol. 2006. PMID 17209776 · DOI
  6. Schwartz JH, Tattersall I. The human chin revisited: what is it and who has it?. J Hum Evol. 2000. PMID 10683306 · DOI
  7. Ewing M, Ross RB. Soft tissue response to mandibular advancement and genioplasty. Am J Orthod Dentofacial Orthop. 1992. PMID 1598895 · DOI
  8. Park HS, Ellis E, Fonseca RJ, Reynolds ST, Mayo KH. A retrospective study of advancement genioplasty. Oral Surg Oral Med Oral Pathol. 1989. PMID 2654795 · DOI
  9. Vanaman Wilson MJ, Jones IT, Butterwick K, Fabi SG. Role of Nonsurgical Chin Augmentation in Full Face Rejuvenation: A Review and Our Experience. Dermatol Surg. 2018. PMID 29309340 · DOI
  10. Deschamps-Braly J. Feminization of the Chin: Genioplasty Using Osteotomies. Facial Plast Surg Clin North Am. 2019. PMID 30940390 · DOI

About this article

Sources
NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
Verification
Every reference was resolved against PubMed on 2026-10-31; title, year and DOI matched.
Review state
automated source verified; no human expert review has been recorded yet.
Version
1, last updated 2026-10-31.

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At a glance

4,318
PubMed records on this heading
11%
published since 2020
233
review articles
106
randomized trials
10
verified references below

Counts come from PubMed on 2026-10-31; they show how much has been written, not how strong the evidence is.

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